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黃舒宜助理研究員

▍聯繫資訊
  • 辦公室：第六共研
  • 電話：院內分機 263250
  • Email：shuyih@ntuh.gov.tw
  • 實驗室網站：（建置中）

 

▍學歷
  • Ph.D., Genes and Development, University of Texas Southwestern Medical Center
  • M.S., Zoology, University of Hawaii at Manoa
  • B.S., Zoology, National Taiwan University

 

 許家郎助理研究員
▍經歷
  • Postdoctoral Researcher, Dr. Beth Levine's Lab, UT Southwestern
  • Postdoctoral Researcher, Dr. Rueyling Lin's Lab, UT Southwestern

 

▍主要專長
  • 細胞學
  • 分子生物學
  • 線蟲遺傳學
  • 發育生物學

 

▍研究方向
  • 細胞鞘脂(sphingolipids)平衡通過影響細胞膜及胞器的膜組成，對於胞內體運輸、氧化壓力、自噬活性及外泌體生成所造成的影響及其分子機制。

 

▍近五年論文發表
  • Fei-Yang Tzou, Pei-Huan Chuang, Chia-Heng Hsu, Chih-Hsuan Wu, Yi Hsiao, Chung-Chih Liu, Yu-Lian Yu, Yu-Han Yeh, Chih-Wei Lin, Chih-Chaing Chan, Shu-Yi Huang (2025, Jun). Dihydroceramide desaturase modulates autolysosome maturation and ameliorates CRB1 retinopathy. Biochimica et biophysica acta - Molecular basis of disease, 1871(5):167736. DOI: http://doi.org/10.1016/j.bbadis.2025.167736.
  • Ying-Yi Chen, Chung-May Yang, Chang-Hao Yang, Tzyy-Chang Ho, Yi-Ting Hsieh, Tso-Ting Lai, Tzu-Hsun Tsai*, and Shu-Yi Huang* (2025, Feb). Elevated Very-Long-Chain Ceramides in the Vitreous Humor of Patients With Proliferative Diabetic Retinopathy. Investigative ophthalmology & visual science, 66(2):28. DOI: http://doi.org/10.1167/iovs.66.2.28. (* Co-corresponding authors)
  • Kah Yong Goh, Wen Xing Lee, Sze Mun Choy, Gopal Krishnan Priyadarshini, Kenon Chua, Qian Hui Tan, Shin Yi Low, Hui San Chin, Chee Seng Wong, Shu-Yi Huang, Nai Yang Fu, Jun Nishiyama, Nathan Harmston, Hong-Wen Tang (2024, Jul). FOXO-regulated DEAF1 controls muscle regeneration through autophagy. Autophagy, 20:1-23. DOI: http://doi.org/10.1080/15548627.2024.2374693.
  • Jui-Yu Yeh, Hua-Chuan Chao, Cheng-Li Hong, Yu-Chien Hung, Fei-Yang Tzou, Cheng-Tsung Hsiao, Jeng-Lin Li, Wen-Jie Chen, Cheng-Ta Chou, Yu-Shuen Tsai, Yi-Chu Liao, Yu-Chun Lin, Suewei Lin, Shu-Yi Huang, Marina Kennerson, Yi-Chung Lee, Chih-Chiang Chan (2024, May). A missense mutation in human INSC causes peripheral neuropathy. EMBO Molecular Medicine, 16(5):1091-1114. DOI: http://doi.org/10.1038/s44321-024-00062-w.
  • Shi-Yao Wei, Yu-Hsiang Chou, Fan-Chi Chang, Shu-Yi Huang, Chun-Fu Lai, Shuei-Liong Lin (2024, Feb). Young Plasma Attenuated Chronic Kidney Disease Progression after Acute Kidney Injury by Inhibiting inflammation in Mice. Aging and Disease, AD.2023.1230. DOI: http://doi.org/10.14336/AD.2023.1230.
  • Fei-Yang Tzou, Thorsten Hornemann, Jui-Yu Yeh, Shu-Yi Huang (2023, May). The pathophysiological role of dihydroceramide desaturase in the nervous system. Progress in Lipid Research, 91:101236. DOI: http://doi.org/10.1016/j.plipres.2023.101236.
  • Chen-Yi Wu, Jhih-Gang Jhang, Wan-Syuan Lin, Pei-Huan Chuang, Chih-Wei Lin, Li-An Chu, Ann-Shyn Chiang, Han-Chen Ho, Chih-Chiang Chan*, Shu-Yi Huang* (2021, Nov). Dihydroceramide desaturase promotes the formation of intraluminal vesicles and inhibits autophagy to increase exosome production. iScience, 2021:103437. DOI: https://doi.org/10.1016/j.isci.2021.103437. (* Co-corresponding authors)
  • Yu-Chien Hung, Kuan-Lin Huang, Po-Lin Chen, Jeng-Lin Li, Serena Huei-An Lu, Jui-Chih Chang, Han-Yi Lin, Wen-Chun Lo, Shu-Yi Huang, Tai-Ting Lee, Tai-Yi Lin, Yuzuru Imai, Nobutaka Hattori, Chin-San Liu, Su-Yi Tsai, Chun- Hong Chen, Chin-Hsien Lin, Chih-Chiang Chan (2021, Sep). UQCRC1 engages cytochrome c for neuronal apoptotic cell death. Cell Reports, 36(12), 109729. DOI: https://doi.org/10.1016/j.celrep.2021.109729.
  • Fei-Yang Tzou, Tsu-Yi Su, Wan-Syuan Lin, Han-Chun Kuo, Yu-Lian Yu, Yu-Han Yeh, Chung-Chih Liu, Ching-Hua Kuo, Shu-Yi Huang, Chih-Chiang Chan. Dihydroceramide desaturase regulates the compartmentalization of Rac1 for neuronal oxidative stress. Cell Reports, 35(2), 108972. DOI: https://doi.org/10.1016/j.celrep.2021.108972.
  • Wen-Yu Lien, Yu-Ting Chen, Yi-Jhan Li, Jie-Kai Wu, Kuan-Lin Huang, Jian-Rong Lin, Shih-Ching Lin, Chia-Chun Hou, Horng-Dar Wang, Chia-Lin Wu, Shu-Yi Huang, Chih-Chiang Chan (2020, Jul). Lifespan regulation in α/β posterior neurons of the fly mushroom bodies by Rab27. Aging Cell, 19(8):e13179. DOI: https://doi.org/10.1111/acel.13179.
  • Wei-Hung Jung, Chung-Chih Liu, Yu-Lian Yu, Yu-Chin Chang, Wen-Yu Lien, His-Chun Chao, Shu-Yi Huang, Ching-Hua Kuo, Han-Chen Ho, and Chih-Chiang Chan (2017, Jul). Lipophagy prevents activity-dependent neurodegeneration due to dihydroceramide accumulation in vivo. EMBO reports, 18(7):1150-1165. DOI: http://doi.org/10.15252/embr.201643480.