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本部研究

研究概況
本部研究的主要方向,包括:思覺失調症的早期發現與治療、思覺失調症前驅症狀探討、思覺失調症的遺傳與電生理研究、全國自殺防治研究、兒童青少年自閉症、注意力不足過動症、睡眠障礙研究、心身醫學與睡眠醫學、飲食障礙症、老年精神醫學、司法精神醫學與精神醫療政策、精神流行病學、精神醫學資訊學等,研究成果在國內與國外,佔有十分重要的地位。本部2019年主治醫師擔任主持人的研究計畫有30件,在國內外論文發表57篇,其中高淑芬教授、黃宗正醫師、吳建昌醫師、商志雍醫師醫師多次受邀在國際研討會演講。以下選錄由本部主治醫師主持之研究計畫、2019年科部同仁出版論文、以及2019年研究榮譽獲獎記錄以供參考。
團隊會議

2019 發表論文一覽

一般精神科團隊研究論文

  1. Wu KCC, Addressing disability in global mental health and neuroethics: Challenge and hopes, in Dan Stein and Ilina Singh eds., Global mental health and neuroethics, 2019, London: Elsevier, 237-262 [吳建昌]
  2. 吳建昌,成癮、心智科學與刑事責任能力,李茂生教授祝壽論文集(編輯中)。
  3. 丁碩彥(共同第一作者)、吳建昌(共同第一作者)、簡以嘉、胡海國,精神醫療的公共衛生政策,撥雲見日-龍發堂現象及其社會意義,高雄市:高雄市衛生局,2019年11月,頁184-173。
  4. Wu KCC, A Philosophical Anthropology reflection on Motoko Kusanagi in Ghost in the shell, 5 Designing Media Ecology, Dec., 2018, 42-51 [吳建昌]
  5. Hsieh MH, Lin YT, Chien YL, Hwang TJ, Hwu HG, Liu CM, Liu CC,Auditory Event-Related Potentials in Antipsychotic-Free Subjects with Ultra-High Risk State and First-Episode Psychosis. Frontiers in Psychiatry 2019 Apr 15;10:223 [謝明憲、林奕廷、簡意玲、黃宗正、胡海國、劉智民、劉震鐘]
  6. Chen HY, Ma CH, Liu CC. Two cases of de novo pathological gambling associated with aripiprazole. Clinical Neuropharmacology 2019;42: 101–102 [陳惠怡、馬家豪、劉震鐘]
  7. Liu CC, Lin YT, Liu CM, Hsieh MH, Chien YL, Hwang TJ, Hwu HG. Trajectories after first-episode psychosis: Complement to ambiguous outcomes of long-term antipsychotic treatment by exploring a few hidden cases. Early Intervention in Psychiatry 2019;13:895–901. [劉震鐘、林奕廷、劉智民、謝明憲、簡意玲、黃宗正、胡海國]
  8. Liu CC & Takeuchi H. Achieving the Lowest Effective Antipsychotic Dose for Patients with Remitted Psychosis: A Proposed Guided Dose&Reduction Algorithm. CNS Drugs [Epub ahead of print] [劉震鐘]
  9. Wang YC, Lin YT, Liu CM, Hwang TJ, Hsieh MH, Chien YL, Hwu HG, Liu CC. Stigmas toward psychosis-related clinical features among the general public in Taiwan. Asia-Pacific Psychiatry [Epub ahead of print]  [王彥欽、林奕廷、劉智民、黃宗正、謝明憲、簡意玲、胡海國、劉震鐘]
  10. Chien YL, Hsieh MH, Gau SS. P50-N100-P200 sensory gating deficits in adolescents and young adults with autism spectrum disorders. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2019 Dec 20;95:109683. [謝明憲、簡意玲、高淑芬]
  11. Chien YL, Chou MC, Chou WJ, Wu YY, Tsai WC, Chiu YN, Gau SS. Prenatal and perinatal risk factors and the clinical implications on autism spectrum disorder. Autism. 2019 Apr;23(3):783-791. [簡意玲、蔡文哲、高淑芬]
  12. Lo YC, Chen YJ, Hsu YC, Chien YL, Gau SS, Tseng WI. Altered frontal aslant tracts as a heritable neural basis of social communication deficits in autism spectrum disorder: A sibling study using tract-based automatic analysis. Autism Research. 2019 Feb;12(2):225-238. [簡意玲、高淑芬]
  13. Liu CM, Liu YL, Hwu HG, Fann CS, Yang UC, Hsu PC, Chang CC, Chen WJ, Hwang TJ, Hsieh MH, Liu CC, Chien YL, Lin YT, Tsuang MT. Genetic associations and expression of extra-short isoforms of disrupted-in-schizophrenia 1 in a neurocognitive subgroup of schizophrenia. Journal of Human Genetics. 2019 Jul;64(7):653-663 [劉震鐘、林奕廷、劉智民、謝明憲、簡意玲、黃宗正、胡海國]
  14. Wang SH, Hsiao PC, Yeh LL, Liu CM, Liu CC, Hwang TJ, Hsieh MHChien YL, Lin YT, Huang YT, Chen CY, Chandler SD, Faraone SV, Neale B, Glatt SJ, Tsuang MT, Hwu HG, Chen WJ. Advanced paternal age and early onset of schizophrenia in sporadic cases: not confounded by parental polygenic risk for schizophrenia. Biological Psychiatry. 2019 Jul 1;86(1):56-64. [劉震鐘、林奕廷、劉智民、謝明憲、簡意玲、黃宗正]
  15. Lin YT, Lu TS, Hansen RA, Wang CC. Selective Serotonin Reuptake Inhibitor Use and Risk of Arrhythmia: A Nationwide, Population-Based Cohort Study. Clin Ther. 2019;41(6):1128-38 e8. [林奕廷]
  16. Lin YT, Liu HH, Hsieh MH. Points that need attention in quantitative EEG gamma synchronization. J Affect Disord. 2019;255:177-8. .[林奕廷、謝明憲]
  17. Chen YL, Tseng WL, Yang LK, Gau SS (2019) Gender and Age Differences in Sleep Problems in Children: Person-Oriented Approach with Multigroup Analysis. Behav Sleep Med. [高淑芬]

兒童精神科團隊研究論文

  1. Seng GJ, Tseng WL, Chiu YN, Tsai WC, Wu YY, Gau SS (2020) Executive functions in youths with autism spectrum disorder and their unaffected siblings. Psychological Medicine  [蔡文哲、丘彥南、高淑芬]
  2. Lin YS, Gau SS, Lee CC** (2020) A multimodal interlocutor-modulated attentional BLSTM for classifying autism subgroups during clinical interviews. IEEE Journal of Selected Topics in Signal Processing[高淑芬]
  3. Chen YY, Chen YL, Gau SS (2020) Suicidality in children with elevated autistic traits. Autism Research [高淑芬]
  4. Lin HY, Ni HC, Tseng WY, Gau SS (2020) Characterizing intrinsic functional connectivity in relations to impaired self-regulation in high-functioning male youth with autism spectrum disorder. Autism [高淑芬]
  5. Lin HY, Kesseler D, Tseng WI, Gau SS (2020) Compensatory functional segregation related to the salience network in unaffected siblings of youths with ADHD. Journal of American Academy of Child and Adolescent Psychiatry [高淑芬]
  6. Shang CY, Lin HY, Gau SS (2020) Effects of the dopamine transporter gene on striatal functional connectivity in youths with attention-deficit/hyperactivity disorder. Psychological Medicine. [高淑芬]
  7. Tsai TH, Chen YL, Gau SS (2019) Relationships between autistic traits, insufficient sleep, and real-world executive function deficits in children: A mediation analysis of a national epidemiological survey Psychological Medicine. [高淑芬]
  8. Shang CY, Shih HH, Pan YL, Lin HY, Gau SS (2019) Comparative Efficacy of Methylphenidate and Atomoxetine on Social Adjustment in Youths with Attention-Deficit/Hyperactivity Disorder. Journal of Child and Adolescent Psychopharmacology. [林祥源、高淑芬]
  9. Hearne L, Lin HY, Sanz-Leon P, Tseng WY, Gau SS, Robert JA, Cocchi L (2019) ADHD symptoms map onto noise-driven structure-function decoupling between hub and peripheral brain regions. Molecular Psychiatry [林祥源、高淑芬]
  10. Shang CY, Lin HY, Gau SS (2019) A haplotype of the norepinephrine transporter gene modulates intrinsic brain activity, visual memory, and visual attention in children with attention-deficit/hyperactivity disorder. Molecular Psychiatry [林祥源、高淑芬]
  11. Ni HC, Lin HY, Chen YC, Tseng WI, Gau SS (2019) Boys with autism spectrum disorder have distinct cortical folding patterns underpinning impaired self-regulation: a surface-based morphometry study. Brain Imaging and Behavior [林祥源、高淑芬]
  12. Chang YC, Chen YL, Gau SS (2019) The mental health of immigrant mother’s offspring in Taiwan: A National epidemiological study. Journal of the Formosan Medical Association (JFMA).2019 Sep 19. [高淑芬]
  13. Chang LY, Lin HY, Gau SS, Lu CY, Hsia SH, Huang YC, Huang LM, Lin TY (2019). Enterovirus A71 neurologic complications and long-term sequelae. Journal of Biomedical Science. [林祥源、高淑芬]
  14. Huang WL, Liao SC, Tu YK, Yang CCH, Kuo TBJ, Gau SS (2019). Autonomic reactivity during reading of a somatic distress script in patients with somatic symptom disorder. Journal of Psychosomatic Research. [高淑芬]
  15. Wong CH, Gau SS Chou TL (2019). Neural correlates of association strength and categorical relatedness in youths with autism spectrum disorder. Autism Research [高淑芬]
  16. Chuang WC, Yeh CB, Wang SC, Pan PY, Shyu JF, Liu YP, Gau SS, Lu RB (2019) Potential negative effects of dextromethorphan as an Add-On therapy to methylphenidate in children with ADHD. Front Psychiatry. [高淑芬]
  17. Chien YL, Hsieh MH, Gau SS (2019) P50-N100-P200 sensory gating deficits in adolescents and young adults with autism spectrum disorders. Prog Neuropsychopharmacol Biol Psychiatry.] [高淑芬]
  18. Chiang HL, Hsu YC, Shang CY, Tseng WY, Gau SS (2019) White matter endophenotype candidates for ADHD: a diffusion imaging tractography study with sibling design, Psychological Medicine [高淑芬]
  19. Lin HY, Perry A, Cocchi L, Roberts JA, Tseng WI, Breakspear M, Gau SS (2019) Development of frontoparietal connectivity predicts longitudinal symptom changes in young people with autism spectrum disorder. Translational Psychiatry [高淑芬]
  20. Hwang-Gu SL, Chen YC, Liang SH, Ni HC, Lin CF, Gau SS (2019) Exploring the variability in reaction times of preschoolers at risk of attention-deficit/hyperactivity disorder: an ex-Gaussian analysis. Journal of Abnormal Child Psychology [高淑芬]
  21. Tsai FJ, Tseng WL, Yang LK, Gau SS (2019) Psychiatric comorbid patterns in adults with attention-deficit hyperactivity disorder: Treatment effect and subtypes. [高淑芬]
  22. Chen YL, Chen WJ, Lin KC, Shen LJ, Gau SS (2019) Prevalence of DSM-5 mental disorders in a nationally representative sample of children in Taiwan: methodology and main findings. Epidemiology and Psychiatric Science [高淑芬]
  23. Chen CP, Gau SS, Lee CC (2019) Toward differential diagnosis of autism spectrum disorder using multimodal behavior descriptors and executive functions. Computer Speech & Language [高淑芬]
  24. Hirota T, Guerrero A, Sartorius N, Gau SS, Skokauska N (2018) Child and adolescent psychiatry in the Far East; a 5-year follow up on the Consortium on Academic Child and Adolescent Psychiatry in the Far East (CACAP-FE) study. Psychiatry and Clinical Neurosciences[高淑芬]
  25. Tsai JM, Lu L, Jeng SF, Cheong PL, Gau SS, Huang YH, Wu YT (2019) Validation of the modified checklist for autism in toddlers, revised with follow-up in Taiwanese toddlers. Research in Developmental Disability [高淑芬]
  26. Lo YC, Chen YJ, Hsu YC, Chien YLGau SS, Tseng WI (2019) Altered frontal aslant tracts as a heritable neural basis of social communication deficits in autism spectrum disorder: A sibling study using tract-based automatic analysis. Autism Research[簡意玲、高淑芬]
  27. Chen YY, Chen YL, Gau SS (2019) Attention-deficit hyperactivity disorder and suicidality: the mediating effects of psychiatric comorbidities and family function. Journal of Affective Disorders [高淑芬]
  28. Shih HH, Shang CY, Gau SS (2019) Comparative Efficacy of Methylphenidate and Atomoxetine on Emotional and Behavioral Problems in Youths with Attention-Deficit Hyperactivity Disorder. Journal of Child and Adolescent Psychopharmacology [高淑芬]
  29. Chang JP, Lai MC, Chou MC, Shang CY, Chiu YN, Tsai WC, Wu YY, Gau SS (2019) Maternal and Family Processes in Different Subgroups of Youth with Autism Spectrum Disorder. Journal of Abnormal Child Psychology. [蔡文哲、丘彥南、高淑芬]
  30. Lin CW, Lin HY, Lo YC, Chen YJ, Hsu YC, Chen YL, Tseng WY, Gau SS (2019) Alterations in white matter microstructures and regional volume are related to motor functions in boys with autism spectrum disorder. Progress in Neuropsychopharmacology & Biological Psychiatry [林祥源、高淑芬]
  31. Chien YL, Chou MC, Chou WJ, Wu YY, Tsai WC, Chiu YNGau SS (2019) Prenatal and perinatal risk factors and the clinical implications on autism spectrum disorder. Autism 2019 [蔡文哲、丘彥南、簡意玲、高淑芬]
  32. Lin YJ, Gau SS (2019) Developmental changes of neuropsychological functioning in individuals with and without childhood ADHD from early adolescence to young adulthood: a 7-year follow-up study. Psychological Medicine [高淑芬]
  33. Hwang-Gu SL, Lin HY, Chen YC, Tseng YH, Hsu WY, Chou MC, Chou WJ, Wu YY, Gau SS (2019) Symptoms of ADHD affect intrasubject variability in youths with autism spectrum disorder: An ex-Gaussian analysis. Journal of Clinical Child & Adolescent Psychology  [林祥源、高淑芬]

心身醫學科團隊研究論文

  1. CY Lin, IM Chen, HJ Tsai, CS Wu, SC Liao, Effectiveness of electroconvulsive therapy on treatment-resistant depressive disorder: A population-based mirror-image study. Journal of Psychiatric Research 2020 Feb. 121, 101-107 [林忠毅、陳宜明、吳其炘、廖士程]
  2. Wu CS, Kuo CJ, Su CH, Wang SH, Dai HJ. Text mining approach to extract depressive symptoms and to validate the diagnosis of major depressive disorder from electronic health records Journal of Affective Disorder 2020 Jan, 260, 617-623  [吳其炘]
  3. Liu SK, Chang JC, Tsai HJ, Wu CS. Comparisons of the clinical outcomes between early- and adult-onset bipolar disorders: a prospective cohort analysis. Journal of Affective Disorder 2020 Jan. 260, 1-10[張鎔麒、吳其炘]
  4. Dai HJ, Wang FD, Su CH, Chen CW, Wu CS. Adverse Drug Event and Medication Extraction in Electronic Health Records via a Cascading Architecture with Different Sequence Labeling Models and Word Embeddings. Journal of the American Medical Informatics Association 2020 Jan. 27(1): 47-55 2019 [吳其炘]
  5. Liu TY, Wu CS, Hsieh MH. Clinical characteristics and outcomes associated with weekend admissions to psychiatric wards in Taiwan. General Hospital Psychiatry Sep/Oct. 2019. 60, 20-26 [劉子瑜、吳其炘、謝明憲]
  6. Chung YCE, Chen HC, Chou HCL, Chen IM, Lee MS, Chuang LC, Liu YW, Lu ML, Chen CH, Wu CS, Huang MC, Liao SC, Ni YH, Lai MS, Shih WL, Kuo PH. Exploration of microbiota targets for major depressive disorder and mood related traits. Journal of Psychiatric Research 2019 Apr.111, 74-82[陳錫中、陳宜明、廖士程、吳其炘]
  7. Wu CS, Chen TY, Tsai SY, Chen CC, Kuo CJ. Estimating the Risk of Pneumonia in Patients with Schizophrenia Newly Receiving Clozapine: A Nationwide Cohort Study. Journal of Clinical Psychopharmacology 2019 Jul/Aug. 39(4):297-304[吳其炘]