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Hepatitis Research Center > Principle investigators > Wu-Hui-Lin
principle investigators
Hui-Lin Wu

Hui-Lin Wu

Associate Research Fellow

 

 

Fields of specialty

Virology

Molecular biology

 

Current Position

Associate Research Fellow, Hepatitis Research Center, National

Taiwan University Hospital, 1993-

 

Education

Bachelor of Science in Microbiology: Department of

   Microbiology, Soochow University, Taiwan.

Master of Science (1984-1986): Department of Microbiology

   and Immunology, National Taiwan University, Taiwan.

Master of Public Health (1987-88): The Johns Hopkins

   University School of Hygiene and Public Health, USA.

Ph.D. (1988-1992): Department of Immunology and Infectious

   Diseases, The Johns Hopkins University School of Hygiene

   and Public Health, USA.

 

Honors and Affiliations

Scholarship for studying abroad awarded by the Ministry of

Education

Member of Phi-Tau-Phi scholastic honor society (elected in 1984)

Member of the Alpha Chapter of Omega, the National Honorary

Public Health Society (elected in 1987)

 

Research interest

The research of her laboratory mainly focuses on establishing animal models for chronic hepatitis B to study pathogenesis of chronic hepatitis B and develop novel therapeutic strategies to treat diseases associated with chronic HBV infection.

A. To establish woodchuck animal model for chronic hepatitis B

(1) Hepatitis research center has imported woodchucks from

the United States since 1998 and has established this

model in Taiwan.

(2) Using woodchuck hepatitis virus (WHV)-infected

woodchucks to study the pathogenesis of chronic hepatitis

B as well as to evaluate the efficacy and safety of new

therapeutic strategies for chronic hepatitis B and related

hepatocellular carcinoma preclinically.

B. To explore the feasibility of using RNA interference-based

strategy to control viral expression, replication and infection.