Clinical Diagnostic Criteria of Frontotemporal Dementia (FTD)
Based on the foregoing, the recommended clinical criteria for diagnosing FTD are
□ (1). The development of behavioral or cognitive deficits manifested by either
□ (a). early and progressive change in personality, characterized by difficulty in modulating behavior, often resulting in appropriate response or activities, or
□ (b). early and progressive change in language, characterized by problems with expression of language or severe naming difficulty and problems with word meaning
□ (2). The deficits outlined in 1a or 1b cause significant impairment in social or occupational functioning and represent a significant decline from a previous level of functioning.
□ (3). The course is characterized by a gradual onset and continuing decline in function
□ (4). The deficits outlined in 1a or 1b are not due to other nervous system conditions (eg. hypothyroidism), or substances-induced condition.
□ (5). The deficits do not occurr exclusively during a delirium.
□ (6) The disturbance is not better accounted for by a psychiatric diagnosis (eg.depression)
Adapted from Work Group on Frontotempotal Dementia and Pick’s Disease, McKhann et. al.; Arch Neurol. 2001