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Clinical Professor Chin-Hsien Lin publication

林靜嫻臨床教授(Chin-Hsien Lin)

  • Lee MJ, Mata IF, Lin CH, Tzen KY, Lincoln SJ, Bounds R, Lockhart  PJ, Hulihan MM, Farrer MJ, Wu RM. Genotype-Phenotype correlates in  Taiwanese patients with early-onset recessive parkinsonism. Mov  Disord. 2009; 15;24(1):104-8. (SCI)

 

  • Tai CH, Yen RF, Lin CH, Yen KY, Yip PK, Wu RM, Lee MJ. Focal brain  glucose hypermetabolism in myoclonus-dystonia syndrome caused by an epsilon-sarcoglycan gene mutation. Parkinsonism Relat Disord.  2009;15(8):614-6 (SCI)

 

  • Ross OA, Spanaki C, Griffith A, Lin CH, Kachergus J, Haugarvoll K,  Latsoudis H, Plaitakis A, Ferreira JJ, Sampaio C, Bonifati V, Wu RM,  Zabetian CP, Farrer MJ. Haplotype analysis of Lrrk2 R1441H carriers  with parkinsonism. Parkinsonism and Related Disorders.  2009;15(6):466-7. (SCI)

 

  • Taylor JM, Wu RM, Lin CH, Delatycki MB, Lockhart PJ. Lack of  evidence for association of a parkin promoter polymorphism with  early-onset Parkinson's disease in a Chinese population. Parkinsonism  and Related Disorders. 2009;15(2):149-52. (SCI)

 

  • Eng-King Tan, Chin-Hslen Lin, Chun-Hwei Tai, Louis C. Tan,  Meng-Ling Chen, R. Li, Hui-Qin Lim, Ratnagopal Pavanni, Yih Yuen, K.  M. Prakash, Yi Zhao, Ruey-Meei Wu. Non-synonymous GIGYF2 variants in  Parkinson's disease from two Asian populations. Hum Genet. 2009 May  16. [Epub ahead of print] (SCI)

 

  • Hoi-Fong Chan, Meng-Ling Chen, Jen-Jen Su, Li-Chin Ko, Chin-Hsien  Lin*(corresponding author), Ruey-Meei Wu. A novel neuropsychiatric  phenotype of KCNJ2 mutation in one Taiwanese family with  Andersen-Tawil syndrome. J Hum Genetics 2010 Mar;55(3):186-8. (SCI)

 

  • Tai CH, Wu RM, Lin CH, Pan MK, Chen YF, Liu HM, Lu HH, Tsai CW,  Tseng SH. Deep brain stimulation therapy for parkinson's disease using  frameless stereotaxy: comparison with frame-based surgery. Eur J  Neurol. 2010 Apr 23. [Epub ahead of print] PMID: 20443976 [PubMed - as  supplied by publisher] (SCI)

 

  • Tan EK, Peng R, Teo YY, Tan LC, Angeles D, Ho P, Chen ML, Lin CH,  Mao XY, Chang XL, Prakash KM, Liu JJ, Au WL, Le WD, Jankovic J,  Burgunder JM, Zhao Y, Wu RM. Multiple LRRK2 variants modulate risk of  Parkinson disease: a Chinese multicenter study. Hum Mutat. 2010  May;31(5):561-8. (SCI)

 

  • Yu RL, Wu RM, Tai CH, Lin CH, Hua MS. Feeling-of-knowing in  episodic memory in patients with Parkinson's disease with various  motor symptoms. Mov Disord. 2010;25(8):1034-9. (SCI)

 

  • Chin-Hsien Lin, Pei-I Tsai, Ruey-Meei Wu, Cheng-Ting Chien. LRRK2  G2019S Mutation Induces Dendrite Degeneration through Mislocalization  and Phosphorylation of Tau by Recruiting Autoactivated GSK3. J  Neurosci 2010;30(39):13138-49. (SCI)

 

  • Yu-Ren Chen, Ya-Ping Huang, Shan-Ju, Lin, Tsao-Hsiang Kuan,  Chin-Hsien Lin* (corresponding author). Effectiveness of Quetiapine  for Post-Stroke Pathological Laughing: Case Report and Review of the  Literature. Clinical Neuropharmacology 2010 Nov-Dec;33(6):319-22.

 

  • Huang,SL; Hsieh,CL; Wu,RM; Tai,CH; Lin,CH; Lu,WS . Minimal Detectable Change of       the Timed ""Up & Go"" Test and the Dynamic Gait Index in People With Parkinson      Disease. Pysical Therapy 2011  JAN;91 (1) :114-121

 

  • Lin,CH; Chen,ML; Chen,GS; Tai,CH; Wu,RM. Novel variant Pro143Ala in HTRA2  contributes to Parkinson's disease by inducing  hyperphosphorylation of HTRA2 protein in mitochondria. Human Genetics 2011 Dec;130 (6) :817-827

 

  • Lin,CH; Wu,RM; Tai,CH; Chen,ML; Hu,FC . Lrrk2 S1647T and BDNF V66M interact  with environmental factors to  increase risk of Parkinson's disease. Parkinsonism & Related      Disorders,2011 Feb;17 (2) :84-88

 

  • Ross,OA; Soto-tolaza,AI; Heckman,MG; Aasly,JO; Abahuni,N; Annesi,G; Bacon,JA;       Bardien,S; Bozi,M; Brice,A; Brighina,L; VanBroeckhoven,C;Carr,J; Chartier-Harlin,MC;       Dardiotis,E; Dickson,DW; Diehl,NN; Elbaz,A; Ferrarese,C; Ferraris,A; Fiske,B;       Gibson,JM; Gibson,R; Hadjigeorgiou,GM; Hattori,N;Ioannidis,JPA; Jasinska-Myga,B;       Jeon,BS; Kim,YJ; Klein,C; Kruger,R; Kyratzi,E;Lesage,S; Lin,CH; Lynch,T;       Maraganore,DM; Mellick,GD; Mutez,E; Nilsson,C;Opala,G; Park,SS; Puschmann,A;       Quattrone,A; Sharma,M; Silburn,PA; Sohn,YH;Stefanis,L; Tadic,V; Theuns,J;       Tomiyama,H; Uitti,RJ; Valente,EM; vandeLoo,S;Vassilatis,DK; Vilarino-Guell,C;       White,LR; Wirdefeldt,K; Wszolek,ZK; Wu,RM; Farrer,MJ . Association of LRRK2 exonic variants with susceptibility to Parkinson's   disease: a case-control study. Lancet Neurology 2011 Oct;10 (10) :898-908

 

  • Yen,CY; Lin,KH; Hu,MH; Wu,RM; Lu,TW; Lin,CH .Effects of Virtual eality-Augmented       Balance Training on Sensory Organization and Attentional Demand for Postural Control in  People With Parkinson Disease: A Randomized Controlled Trial. Physical Therapy 2011   Jun;91 (6) :862-874

 

  • Kai-Hsiang Chen, Chin-Hsien Lin*(corresponding author), Ruey-Meei Wu.  Psychotic-Affective Symptoms and Multiple System Atrophy Expand Phenotypes of  Spinocerebellar Ataxia Type 2. BMJ Case Reports 2012, Mar 20; in press. 

 

  • Rwei-Ling Yu, Ruey-Meei Wu, Chun-Hwei Tai, Chin-Hsien Lin, Ting-Wen Cheng,  Mau-Sun Hua* Neuropsychological profile in patients with early stage of Parkinson's disease in Taiwan. Parkinsonism Relat Disord. 2012, Jun 30; in press.

 

  • Meng-Chen Wu, Ruoh-Fang Yen, Chin-Hsien Lin*(corresponding author),  Ruey-Meei Wu. Hemiballism in a Patient with Parietal Lobe Infarction. Neurology,  2012, in press.

 

  • Yu RL, Wu RM, Chiu MJ, Tai CH, Lin CH, Hua MS. Advanced Theory of Mind in patients at early stage of Parkinson's disease.Parkinsonism Relat Disord.2012;18(1):21-4.

 

  • Chen KH, Lin CH*, Wu RM. Psychotic-affective symptoms and multiple system atrophy expand phenotypes of spinocerebellar ataxia type 2.BMJ Case Rep. 2012 Mar 20;doi:pii: bcr1020115061.

 

  • Yu RL, Wu RM, Tai CH, Lin CH, Cheng TW, Hua MS. Neuropsychological profile in patients with early stage of Parkinson's disease in Taiwan. Parkinsonism Relat Disord.2012;18(10):1067-72.

 

  • Lai HJ, Lin CH*, Wu RM. Early-onset autosomal-recessive parkinsonian-pyramidal syndrome. Acta Neurol Taiwan. 2012 Sep;21(3):99-107.

 

  • 65.Lin CH, Chen ML, Tai YC, Yu CY, Wu RM. Reaffirmation of GAK, but not HLA-DRA, as a Parkinson's disease susceptibility gene in a Taiwanese population. Am J Med Genet B Neuropsychiatr Genet. 2013 Sep 3. doi: 10.1002/ajmg.b.32188. [Epub ahead of print]

 

  • Lee YC※, Lin CH※(co-first author), Wu RM, Lin MS, Lin JW, Chang CH, Lai MS.Discontinuation of statin therapy associates with Parkinson disease: a population-based study. Neurology. 2013 Jul 30;81(5):410-6.

 

  • Lin CH, Wu RM, Chang HY, Chiang YT, Lin HH. Preceding pain symptoms and Parkinson's disease: a nationwide population-based cohort study. Eur J Neurol. 2013 Oct;20(10):1398-404.

 

  • Lin CH, Chen ML, Yu CY, Wu RM.RIT2 variant is not associated with Parkinson's disease in a Taiwanese population. Neurobiol Aging. 2013 Sep;34(9):2236.e1-3.

 

  • Lin CH, Wu VC, Li WY, Sy HN, Wu SL, Chang CC, Chiu PF, Lion HH, Lin CY, Chang HW, Lin SY, Wu KD, Chen YM, Wu RM. Restless legs syndrome in end-stage renal disease: a multicenter study in Taiwan. Eur J Neurol. 2013 Jul;20(7):1025-31.

 

  • Lin CH, Chen ML, Lai TT, Tai CH, Wu RM. Mutational analysis of FBXO7 gene in Parkinson's disease in a Taiwanese population. Neurobiol Aging. 2013 Jun;34(6):1713.e1-4.

 

  • Wu MC, Yen RF, Lin CH (corresponding author), Wu RM. Hemiballism in a patient with parietal lobe infarction. Neurology. 2013 Jan 15;80(3):e22.

 

  • Lin CH, Ou YK, Wu RM, Liu YC. Predictors of road crossing safety in pedestrians with Parkinson's disease. Accid Anal Prev. 2013 Mar;51:202-7.

 

  • Chen ML, Lin CH, Lee MJ, Wu RM. BST1 rs11724635 interacts with environmental factors to increase the risk of Parkinson's disease in a Taiwanese population. Parkinsonism Relat Disord. 2013 Nov 20. pii: S1353-8020(13)00402-1. doi: 10.1016/j.parkreldis.2013.11.009. [Epub ahead of print]

 

  • Heckman MG, Soto-Ortolaza AI, Aasly JO, Abahuni N, Annesi G, Bacon JA, Bardien S, Bozi M, Brice A, Brighina L, Carr J, Chartier-Harlin MC, Dardiotis E, Dickson DW, Diehl NN, Elbaz A, Ferrarese C, Fiske B, Gibson JM, Gibson R, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Boczarska-Jedynak M, Jasinska-Myga B, Jeon BS, Kim YJ, Klein C, Kruger R, Kyratzi E, Lesage S, Lin CH, Lynch T, Maraganore DM, Mellick GD, Mutez E, Nilsson C, Opala G, Park SS, Petrucci S, Puschmann A, Quattrone A, Sharma M, Silburn PA, Sohn YH, Stefanis L, Tadic V, Theuns J, Tomiyama H, Uitti RJ, Valente EM, Van Broeckhoven C, van de Loo S, Vassilatis DK, Vilariño-Güell C, White LR, Wirdefeldt K, Wszolek ZK, Wu RM, Hentati F, Farrer MJ, Ross OA; Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium. Population-specific frequencies for LRRK2 susceptibility variants in the Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium. Mov Disord. 2013 Oct;28(12):1740-4. doi: 10.1002/mds.25600. Epub 2013 Aug 2.

 

  • Lee YC※, Lin CH※(co-first author), Lin MS, Lin JW, Chang CH, Lai MS. Effects of selective serotonin reuptake inhibitors versus tricyclic antidepressants on cerebrovascular events: a nationwide population-based cohort study. J Clin Psychopharmacol. 2013 Dec;33(6):782-9.

 

  • Chen KH, Lin CH(corresponding author). Brain abscess as an initial presentation in a patient of hereditary haemorrhagic telangiectasia caused by a novel ENG mutation. BMJ Case Rep. 2013 Feb 25;2013. pii: bcr2013008802. doi: 10.1136/bcr-2013-008802.

 

  • Liu WM, Lin CH(corresponding author). A reversible stroke-like splenial lesion in viral encephalopathy. Acta Neurol Taiwan. 2013 Sep;22(3):117-21.

 

  • Michael G. Heckman, Alexis Elbaz, Alexandra I. Soto-Ortolaza, Daniel J. Serie, Jan O. Aasly, Grazia Annesi, Georg Auburger, Justin A. Bacon, Magdalena Boczarska-Jedynak, Maria Bozi, Laura Brighina, Marie-Christine Chartier-Harlin, Efthimios Dardiotis, Alain Destée, Carlo Ferrarese, Alessandro Ferraris, Brian Fiske, Suzana Gispert, Georgios M. Hadjigeorgiou, Nobutaka Hattori, John P. A. Ioannidis, Barbara Jasinska-Myga, Beom S. Jeon, Yun Joong Kim, Christine Klein, Rejko Kruger, Elli Kyratzi, Chin-Hsien Lin, Katja Lohmann, Marie-Anne Loriot PharmD, Timothy Lynch, George D. Mellick, Eugénie Mutez, Grzegorz Opala, Sung Sup Park, Simona Petrucci, Aldo Quattrone, Manu Sharma, Peter A. Silburn, Young Ho Sohn, Leonidas Stefanis, Vera Tadic, Hiroyuki Tomiyama, Ryan J. Uitti, Enza Maria Valente, Demetrios K. Vassilatis, Carles Vilariño-Güell, Linda R. White, Karin Wirdefeldt, Zbigniew K. Wszolek, Ruey-Meei Wu, Georgia Xiromerisiou, Demetrius M. Maraganore, Matthew J. Farrer, Owen A. Ross* on behalf of the Genetic Epidemiology Of Parkinson's Disease (GEO-PD) Consortium. The protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants. Neurobiology of Aging 2014 Jan;35(1):266.e5-266.

 

  • Chin-Hsien Lin, Kai-Hsiang Chen, Meng-Ling Chen, Han-I Lin, Ruey-Meei Wu. Vitamin D receptor genetic variants and Parkinson's disease in a Taiwanese population. Neurobiology of Aging 2014 May;35(5):1212.e11-3

 

  • Chin-Hsien Lin, Meng-Ling Chen, Vin-Cent Wu, Wen-Yi Li, Hiu-Ngar Sy, Shey-Lin Wu; Chia-Chu Chang, Ping-Fang Chiu, Hung-Hsiang Liou, Chien-Yu Lin, Hong-Wei Chang, Sen-Yong Lin, Kwan-Dun Wu, Yung-Ming Chen, Ruey-Meei Wu. Association of candidate genetic variants with restless legs syndrome in end stage renal disease: a multicenter case-control study in Taiwan. European Journal of Neurology 2014 Mar;21(3):492-8.

 

  • Chin-Hsien Lin, Han-I Lin, Ruey-Meei Wu. The p.L302P mutation of lysosomal enzyme gene SMPD1 is rare in Taiwanese Parkinson's disease. Neurology. 2014 Jan 21;82(3):283.

 

  • Chin-Hsien Lin, Ta-Fu Chen, Ming-Jang Chiu, Ruey-Meei Wu. Lack of C9orf72 repeat expansion in Taiwanese patients with mixed neurodegeneratiave disorders. Frontiers in Neurology 2014 Apr 28;5:59.

 

  • Yu-Wen Cheng, Chin-Hsien Lin*, Ruey-Meei Wu. HIV-associated Parkinsonism Reversed with Antiretroviral Therapy. Neurology Asia 2014, accepted.

 

  • Meng-Chen Wu, Chin-Hsien Lin*. Cauda Equina-Conus Medullaris Syndrome as an Isolated Presenting Symptom of Intravascular Large B-cell Lymphoma: Case Report and Review of the Literature. Neurology Asia2014, accepted.

 

  • Yen-Chieh Lee, Chin-Hsien Lin (co-first author), Ruey-Meei Wu, Jou-Wei Lin, Chia-Hsuin Chang, Mei-Shu Lai. Antihypertensive Agents and Risk of Parkinson's disease: A nationwide cohort study. PLOS One 2014 Jun 9;9(6):e98961

 

  • Chang CH, Lin JW, Lin CH, Chen HC, Hwang JJ, Lai MS. Effectiveness and safety of extracranial carotid stent placement: A nationwide self-controlled case-series study. J Formos Med Assoc 2014 Jun 10. pii: S0929-6646(14)00153-3.

 

  • Chin-Hsien Lin, Hiu-Ngar Sy, Hong-Wei Chang, Hung-Hsiang Liou, Chien-Yu Lin, Vin-Cent Wu, Shey-Lin Wu, Chia-Chu Chang, Ping-Fang Chiu, Wen-Yi Li, Sen-Yong Lin, Kwan-Dun Wu, Yung-Ming Chen, Ruey-Meei Wu. Restless legs syndrome is associated with cardio/cerebrovascular events and mortality in end-stage renal disease. European Journal of Neurology 2014 Aug 21. doi: 10.1111/ene.12545.

 

  • Chin-Hsien Lin, Hang-I Lin, Meng-Ling Chen, Ruey-Meei Wu. COQ2 p.V393A variant, rs148156462, is not associated with Parkinson's disease in a Taiwanese population. Neurobiology of Aging 2014 Aug 13. pii: S0197-4580(14)00519-3. doi:

 

  • Chin-Hsien Lin, Jou-Wei Lin, Ying-Chun Liu, Chia-Hsuin Chang, Ruey-Meei Wu. Risk of Parkinson's disease after severe constipation: a nationwide population-based cohort study. Parkinsonism & Related Disorders2014 Sep 28. pii: S1353-8020(14)00363-0. doi: 10.1016/j.parkreldis.2014.09.026

 

  • Chen ML, Wu RM, Tai CH, Lin CH*(corresponding author).Mutational analysis of angiogenin gene in Parkinson's disease. PLoS One 2014 Nov 11;9(11):e112661.

 

  • Chin-Hsien Lin, Hiu-Ngar Sy, Hong-Wei Chang, Hung-Hsiang Liou, Chien-Yu Lin, Vin-Cent Wu, Shey-Lin Wu, Chia-Chu Chang, Ping-Fang Chiu, Wen-Yi Li, Sen-Yong Lin, Kwan-Dun Wu, Yung-Ming Chen, Ruey-Meei Wu. Restless legs syndrome is associated with cardio/cerebrovascular events and mortality in end-stage renal disease. European Journal of Neurology 2015 Jan;22(1):142-9.

 

  • Chin-Hsien Lin, Hang-I Lin, Meng-Ling Chen, Ruey-Meei Wu. COQ2 p.V393A variant, rs148156462, is not associated with Parkinson's disease in a Taiwanese population. Neurobiology of Aging 2015 Jan;36(1):546.e17-8.

 

  • Chin-Hsien Lin, Eng-King Tan, Chih-Chao Yang, Zhao Yi, Ruey-Meei Wu. COQ2 gene variants associate with cerebellar subtype of multiple system atrophy in Chinese. Movement Disorders 2015 Mar;30(3):436-7.

 

  • Lin CH, Wu RM. Biomarkers of cognitive decline in Parkinson's disease. Parkinsonism & Related Disorder 2015 May;21(5):431-43.

 

  • Chin-Hsien Lin, Hsun Li, Yi-Nan Lee, Ying-Ju Cheng, Ruey-Meei Wu, Cheng-Ting Chien. Lrrk regulates the dynamic profile of dendritic Golgi outposts through the golgin Lava lamp. Journal of Cell Biology 2015 Aug 3;210(3):471-83.

 

  • Chin-Hsien Lin, Jou-Wei Lin, Ying-Chun Liu, Chia-Hsuin Chang, Ruey-Meei Wu. Risk of Parkinson's disease following anxiety disorders: A nationwide population-based cohort study. European Journal of Neurology 2015 Sep;22(9):1280-7.

 

  • Weng-Ming Liu, Ruey-Meei Wu, Jou-Wei Lin, Chia-Hsuin Chang, Chin-Hsien Lin* Time trends in the prevalence and incidence of Parkinson's disease in Taiwan: A nationwide, population-based study. Journal of the Formosan Medical Association 2015 Jun 26. pii: S0929-6646(15)00184-9.

 

  • Chang CH, Lin CH, Caffrey JL, Lee YC, Liu YC, Lin JW, Lai MS. Risk of Intracranial Hemorrhage from Statin Use in Asians: A Nationwide Cohort Study. Circulation. 2015 Jun 9;131(23):2070-8.

 

  • Kai-Hsiang Chen, Ruey-Meei Wu, Hang-I Lin,Chun-Hwei Tai, Chin-Hsien Lin* Mutational analysis of SYNJ1 gene (PARK20) in Parkinson's disease in a Taiwanese population. Neurobiology of Aging 2015 Oct;36(10):2905.e7-8.

 

  • Liu WM, Lin RJ, Yu RL, Tai CH, Lin CH, Wu RM. The impact of nonmotor symptoms on quality of life in patients with Parkinson's disease in Taiwan. Neuropsychiatr Dis Treat. 2015 Nov 11;11:2865-73.