戴春暉臨床助理教授(Chun-Hwei Tai)

• Bouali-Benazzouz R, Tai CH, Chetrit J, Benazzouz A: Intrapallidal injection of 6-hydroxydopamine induced changes in dopamine innervation and neuronal activity of globus pallidus. Neuroscience 164:588-596, 2009

 

• Chen CY, Tai CH, Tsay W, Chen PY, Tien HF: Prediction of fatal intracranial hemorrhage in patients with acute myeloid leukemia. Ann Oncol 20:1100-1104, 2009

 

• Tai CH, Yen RF, Lin CH, Yen KY, Yip PK, Wu RM, et al: Focal brain glucose hypermetabolism in myoclonus-dystonia syndrome caused by an epsilon-sarcoglycan gene mutation. Parkinsonism Relat Disord 15:614-616, 2009

 

• Yu RL, Wu RM, Tai CH, Lin CH, Hua MS: Feeling-of-knowing in episodic memory in patients with Parkinson's disease with various motor symptoms. Movement disorders 25: 1034-1039, 2010 

 

• Tai CH, Wu RM, Lin CH, Pan MK, Chen YF, Liu HM, et al: Deep brain stimulation therapy for parkinson's disease using frameless stereotaxy: comparison with frame-based surgery. European Journal of Neurology (Epub ahead of print on Apr. 23, 2010), 2010

 

• Huang,SL; Hsieh,CL; Wu,RM; Tai,CH; Lin,CH; Lu,WS . Minimal Detectable Change of   the Timed ""Up & Go"" Test and the Dynamic Gait Index in People With Parkinson  Disease. Pysical Therapy 2011  JAN;91 (1) :114-121

 

• Lin,CH; Chen,ML; Chen,GS; Tai,CH; Wu,RM. Novel variant Pro143Ala in HTRA2  contributes to Parkinson's disease by   inducing hyperphosphorylationof HTRA2 protein in  mitochondria. Human Genetics 2011 Dec;130 (6) :817-827

 

• Lin,CH; Wu,RM; Tai,CH; Chen,ML; Hu,FC . Lrrk2 S1647T and BDNF V66M interact with environmental factors to  increase risk of Parkinson's disease.Parkinsonism & Related Disorders,2011 Feb;17 (2) :84-88

 

• Tai,CH; Wu,RM; Liu,HM; Tsai,CW; Tseng,SH. Meige Syndrome Relieved by Bilateral  Pallidal Stimulation With Cycling Mode: Case Report. Neurosurgery 2011 Dec;69 (6) :E1333-E1337

 

• Tai,CH; Yang,YC; Pan,MK; Huang,CS; Kuo,CC. Modulation of subthalamic T-type Ca2+  channels remedies locomotor   deficits in a rat model of Parkinson disease. Journal of  Clinical Investigation 2011 Aug;121 (8) :3289-3305 

 

• Chen CY, Tai CH, Cheng A, Wu HC, Tsay W, Liu JH, Chen PY, Huang SY, Yao M, Tang JL, Tien HF. Intracranial hemorrhage in adult patients with hematological malignancies.. BMC Med. 2012 Aug 29;10:97.

 

• Yu RL, Wu RM, Tai CH, Lin CH, Cheng TW, Hua MS. Neuropsychological profile in patients with early stage of Parkinson's disease in Taiwan.  Parkinsonism Relat Disord. 2012 Dec;18(10):1067-72.

 

• Hwu WL, Muramatsu S, Tseng SH, Tzen KY, Lee NC, Chien YH, Snyder RO, Byrne BJ, Tai CH, Wu RM. Gene therapy for aromatic L-amino acid decarboxylase deficiency.Sci Transl Med. 2012 May 16;4(134):134ra61.

 

• Wang SC, Lee LL, Wang WH, Sung HC, Chang HK, Hsu MY, Chang SC, Tai CH. Psychometric testing of the Chinese evidence-based practice scales. J Adv Nurs.2012 Nov;68(11):2570-7.

 

• Yang YC, Tai CH, Pan MK, Kuo CC. The T-type calcium channel as a new therapeutic target for Parkinson's disease. Pflugers Arch. 2014 Apr;466(4):747-55. doi: 10.1007/s00424-014-1466-6. Epub 2014 Feb 18. PubMed PMID:24531801.

 

• Lin CH, Chen ML, Lai TT, Tai CH, Wu RM. Mutational analysis of FBXO7 gene inParkinson's disease in a Taiwanese population. Neurobiol Aging. 2013Jun;34(6):1713.e1-4. doi: 10.1016/j.neurobiolaging.2012.12.023. Epub 2013 Jan 23.PubMed PMID: 23352116.

 

• Pan MK, Tai CH, Liu WC, Pei JC, Lai WS, Kuo CC. Deranged NMDAergic cortico-subthalamic transmission underlies parkinsonian motor deficits J Clin Invest. 2014 Oct;124(10):4629-41. doi: 10.1172/JCI75587. Epub 2014 Sep 9. PubMed PMID: 25202982; PubMed Central PMCID: PMC4191009.

 

• Yang YC, Tai CH, Pan MK, Kuo CC. The T-type calcium channel as a new therapeutic target for Parkinson's disease. Pflugers Arch. 2014 Apr;466(4):747-55. doi: 10.1007/s00424-014-1466-6. Epub 2014 Feb 18. Review PubMed PMID: 24531801.

 

楊智超臨床助理教授(Chih-Chao Yang)

• Wu MY, Hong JB, Yang CC, Hu SL, Liao YH.Scleromyxedema with myopathy was successfully treated by thalidomide. J Eur Acad Dermatol Venereol. 2009;23:189-190.

 

• Tsai LK, Yang CC, Ting CH, Su Yn, Hwu WL, Li H: Correlation of Survival Motor Neuron Expression in Leukocytes and Spinal Cord in Spinal Muscular Atrophy. J Pediatr 2009;154:303-5.

 

• Sheu JJ, Yuan RY, Yang CC: Predictors for Outcome and Treatment Delay in Patients With Tuberculous Meningitis. Am J Med Sci 2009; 338(2): 134-139.

 

• Chen YM, Yang CC, Wang IH, Hu FR, Jou JR. The effect of interferon beta-1a on optic neuritis relapse in patients with multiple sclerosis. Graefes Arch Clin Exp Ophthalmol. 2010 Feb;248(2):231-5. 

 

• Tsai CF, Yang CC, Yip PK: Neurosarcoidosis affecting spinal cord. J Formos Med Assoc (in press)

 

• Huang,JY; Peng,SF; Yang,CC; Yen,KY; Tzen,KY; Yen,RF . Neuroimaging Findings in a Brain With Niemann-Pick Type C Disease. Journal of the Formosan Medical Association    2011  AUG;110 (8) :537-542

 

• Su,YN; Hung,CC; Lin,SY; Chen,FY; Chern,JPS; Tsai,C; Chang,TS; Yang,CC;Li,H;      Ho,HN; Lee,CN. Carrier Screening for Spinal Muscular Atrophy (SMA) in 107,611 Pregnant  Women during the Period 2005-2009: A Prospective Population-Based  Cohort Study. Plos One 2011 Feb25; 6 (2)

 

• Yang,CC; Chien,YH; Lee,NC; Chiang,SC; Lin,SP; Kuo,YT; Chen,SS; Jong,YJ; Hwu,WL. Rapid progressive course of later-onset Pompe disease in Chinese  patients. Molecular     Genetics And Metabolism 2011 NOV;104 (3) :284-288

 

• Chao CT , Yang CC, Kao TW. Fabry disease: A rare cause of fever of unknown origin. Am J Kidney Dis 2012;59(1):161-162.

 

• Sheu JJ, Hsu CY, Yuan RY, Yang CC. Clinical characteristics and treatment delay of cerebral infarction in tuberous meningitis Intern Med J 2012 Mar;42(3):294-300.

 

• Chien YH, Peng SF, Yang CC , Lee NC, Tsai LK, Huang AC, Su SC, Tseng CC, Hwu WL. Long-term efficacy of miglustat in paediatric patients with Niemann-Pick disease type C. J Inherit Metab Dis. 2013 Jan; 36(1):129-37.

 

• Chen CH, Tang SC, Su YN, Yang CC, Jeng JS: Cardioembolic stroke related to limb-girdle muscular dystrophy 1B. BMC Res Notes. 2013 Jan 29; 6(1): 32 

 

• Pan MK, Huang SC, Lo YC, Yang CC, Cheng TW, Yang CC, Hua MS, Lee MJ, Tseng WY:  Microstructural integrity of cerebral fiber tract in hereditary spastic paraparesis with SPG 11-mutation. Am J Neuroradiol 2013;  34: 990-996

 

陳達夫臨床助理教授(Ta-Fu Chen)

• Lin CL, Chen TF, Chiu MJ, Way TD, Lin JK. Epigallocatechin gallate (EGCG) suppresses beta-amyloid-induced neurotoxicity through inhibiting c-Abl/FE65 nuclear translocation and GSK3 beta activation. Neurobiol Aging. 2009 Jan; 30(1):81-92. 

 

• Chen TF, Lin CC, Chen YF, Liu HM, Hua MS, Huang YC, Chiu MJ. Diffusion tensor changes in patients with amnesic mild cognitive impairment and various dementias. Psychiatrist Research: Neuroimaging. 2009 Jul 15; 173(1):15-21.

 

• Liou HH, Wu CY, Chiu YH, Yen AM, Chen RC, Chen TF, Chen CC, Hwang YC, Wen YR, Chen TH. Mortality of Parkinson's disease by Hoehn-Yahr stage from community-based and clinic series [Keelung Community-based Integrated Screening (KCIS) no. 17)]. J Eval Clin Pract. 2009 Aug; 15(4):587-91.

 

• Chen TF, Chen YF, Tsang TW, Liu HM, Hua MS, Chiu MJ. Executive Dysfunction and Periventricular Diffusion Tensor Changes in Mild Cognitive Impairment and Early Alzheimer Disease. Human brain mapping. 2009 Nov; 30(11):3826-36.

 

• Cheng TW, Chen TF, Yip PK, Hua MS, Yang CC, Chiu MJ. Comparison of behavioral and psychological symptoms of Alzheimer's disease among institution residents and memory clinic outpatients. Int Psychogeriatr. 2009 Dec; 21(6):1134-41.

 

• Chen CC, Chen TF, Hwang YC, Wen YR, Chiu YH, Wu CY, Chen RC, Tai JJ, Chen TH, Liou HH. Different prevalence rates of Parkinson's disease in urban and rural areas: a population-based study in Taiwan. Neuroepidemiology. 2009; 33(4):350-7.

 

• MJ Chiu, CW Lin, CC Chen, TF Chen, YF Chen, HM Liu, CP Chu, HH  Liou, MS Hua. Impaired gist memory in patients with temporal lobe epilepsy and hippocampal sclerosis. Epilepsia.2010 Jun; 51(6):1036-42.

 

• Chen YC, Chen TF, Yip PK, Hu CY, Chu YM, Chen JH. Body mass index (BMI)    at an early age and the risk of dementia. Arch Gerontol Geriatr. 2010 Feb; 50 Suppl 1:S48-52.

 

• Chen TF, Huang RF, Lin SE, Lu JF, Tang MC, Chiu MJ.Folic Acid Potentiates the Effect of Memantine on Spatial Learning and Neuronal Protection in an Alzheimer's Disease Transgenic Model. J Alzheimers Dis. 2010;20(2):607-15.

 

• Chen YC, Chen TF, Yip PK, Hu CY, Chu YM, Chen JH. Body mass index (BMI) at an early age and the risk of dementia. Arch Gerontol Geriatr. 2010 Feb; 50 Suppl 1:S48-52.

 

• Chen,TF; Chiu,MJ; Huang,CT; Tang,MC; Wang,SJ; Wang,CC; Huang,RFS. Changes In       Dietary Folate Intake Differentially Affect Oxidised Lipid  And Mitochondrial DNA    Damage In Various Brain Regions Of Rats In The Absence/Presence Of      Intracerebroventricularly Injected Amyloid Beta-Peptide Challenge. British Journal Of       Nutrition 2011MAY;105 (9) :1294-1302

 

• Chiu,MJ; Horng,HE; Chieh,JJ; Liao,SH; Chen,CH; Shih,BY; Yang,CC; Lee,CL;Chen,TF; Yang,SY; Hong,CY; Yang,HC. Multi-Channel SQUID-Based Ultra-High-Sensitivity In- Vitro Detections  For Bio-Markers Of Alzheimer's Disease Via Immunomagnetic  Reduction. IEEE Transactions On Applied Superconductivity. 2011 JUN;21 (3):477-480

 

• Lee,MJ; Chen,TF; Cheng,TW; Chiu,MJ . rs5848 Variant of Progranulin Gene Is a Risk of   Alzheimer's Disease in   the Taiwanese Population. Neurodegenerative Diseases 2011;8 (4) :216-220

 

• Lin,KP; Chen,SY; Lai,LC; Huang,YL; Chen,JH; Chen,TF; Sun,Y; Wen,LL; Yip,PK;  Chu,YM; Chen,WJ; Chen,YC .Genetic Polymorphisms of a Novel Vascular Susceptibility  Gene, Ninjurin2 NINJ2, Are Associated with a Decreased Risk of Alzheimer's  Disease. Plos One 2011 JUN 6;6 (6)

 

• Wang,WH; Liou,HH; Chen,CC; Chiu,MJ; Chen,TF; Cheng,TW; Hua,MS. ropsychological performance and seizure-related risk factors in patients with temporal lobe epilepsy: A    retrospective cross-sectional study. Epilepsy & Behavior 2011 Dec;22 (4) :728-734

 

• Wu,YY; Cheng,IHJ; Lee,CC; Chiu,MJ; Lee,MJ; Chen,TF; Hsu,JL.Clinical Phenotype of G206D Mutation in the Presenilin 1 Gene in   Pathologically Confirmed Familial  Alzheimer's Disease. Journal Of Alzheimers Disease 2011;25 (1) :145-150

 

• Cheng HC, Sun Y, Lai LC, Chen SY, Lee WC, Chen JH, Chen TF, Chen HH, Wen LL, Yip PK, Chu YM, Chen WJ, Chen YC. Genetic polymorphisms of nerve growth factor receptor (NGFR) and the risk of Alzheimer's disease. J Negat Results Biomed. 2012 Jan 12;11:5.

 

• Chen SY, Chen TF, Lai LC, Chen JH, Sun Y, Wen LL, Yip PK, Chu YM, Chen YC.Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease. J Neuroinflammation. 2012 Jan 24;9:21.

 

• Lin YL, Chen SY, Lai LC, Chen JH, Yang SY, Huang YL, Chen TF, Sun Y, Wen LL, Yip PK, Chu YM, Chen WJ, Chen YC. Genetic polymorphisms of clusterin gene are associated with a decreased risk of Alzheimer's disease. Eur J Epidemiol. 2012 Jan 28. [Epub ahead of print]

 

• Chen YC, Yip PK, Huang YL, Sun Y, Wen LL, Chu YM, Chen TF. Sequence variants of toll like receptor 4 and late-onset Alzheimer's disease. PLoS One. 2012;7(12):e50771.

 

• Chen TF, Tang MC, Chou CH, Chiu MJ, Huang RF. Dose-dependent folic acid and memantine treatments promote synergistic or additive protection against Aβ(25-35) peptide-induced apoptosis in SH-SY5Y cells mediated by mitochondria stress-associated death signals. Food Chem Toxicol. 2013 Dec; 62:538-47

 

• Chiu MJ, Yang SY, Horng HE, Yang CC, Chen TF, Chieh JJ, Chen HH, Chen TC, Ho CS, Chang SF, Liu HC, Hong CY, Yang HC. Combined plasma biomarkers for diagnosing mild cognition impairment and Alzheimer's disease. ACS Chem Neurosci. 2013 Dec 18; 4(12):1530-6.

 

• Chiu MJ, Chen YF, Chen TF, Yang SY, Yang FP, Tseng TW, Chieh JJ, Chen JC, Tzen KY, Hua MS, Horng HE. Plasma tau as a window to the brain-negative associations with brain volume and memory function in mild cognitive impairment and early alzheimer's disease. Hum Brain Mapp. 2013 Oct 15

 

• Weng PH, Chen JH, Chen TF, Sun Y, Wen LL, Yip PK, Chu YM, Chen YC. CHRNA7 polymorphisms and response to cholinesterase inhibitors in Alzheimer's disease. PLoS One. 2013 Dec 31; 8(12):e84059

 

• Cingulum correlates of cognitive functions in patients with mild cognitive impairment and early Alzheimer's disease: a diffusion spectrum imaging study. Lin YC, Shih YC, Tseng WY, Chu YH, Wu MT, Chen TF, Tang PF, Chiu MJ. Brain Topogr. 2014 May; 27(3):393-402.

 

• Lin CH, Chen TF, Chiu MJ, Lin HI, Wu RM. Lack of c9orf72 repeat expansion in taiwanese patients with mixed neurodegenerative disorders. Front Neurol. 2014 Apr 28; 5:59

 

• Sun Y, Lee HJ, Yang SC, Chen TF, Lin KN, Lin CC, Wang PN, Tang LY, Chiu MJ. A nationwide survey of mild cognitive impairment and dementia, including very mild dementia, in Taiwan. PLoS One. 2014 Jun 18;9(6):e100303.

 

• Tzen KY, Yang SY, Chen TF, Cheng TW, Horng HE, Wen HP, Huang YY, Shiue CY, Chiu MJ. Plasma Aβ but not tau is related to brain PiB retention in early Alzheimer's disease. ACS Chem Neurosci. 2014 Sep 17;5(9):830-6

 

• Chang HT, Chiu MJ, Chen TF, Cheng TW, Hua MS. Distinct Patterns and Clinical Implications of Semantic Memory Deterioration Among Patients With MCI. Alzheimer Dis Assoc Disord. 2014 Sep 1. [Epub ahead of print]

 

• Chang YL, Chen TF, Shih YC, Chiu MJ, Yan SH, Tseng WY. Regional Cingulum Disruption, Not Gray Matter Atrophy, Detects Cognitive Changes in Amnestic Mild Cognitive Impairment Subtypes. Chang YL, Chen TF, Shih YC, Chiu MJ, Yan SH, Tseng WY. J Alzheimers Dis. 2014 Sep 3. [Epub ahead of print]

 

• Yang SY, Weng PH, Chen JH, Chiou JM, Lew-Ting CY, Chen TF, Sun Y, Wen LL, Yip PK, Chu YM, Chen YC. Leisure activities, apolipoprotein E e4 status, and the risk of dementia. J Formos Med Assoc. 2014 Nov 4. pii: S0929-6646(14)00269-1.32.3.Shieh-Yueh Yang*, Ming-Jang Chiu, Ta-Fu Chen, Chin-Hsien Lin

 

• Jiann-Shing Jeng, Sung-Chun Tang, Yen-Fu Lee, Che-Chuan Yang, Bing-Hsien Liu, Hsin-Hsien Chen, and Chau-Chung Wu. Analytical performance of reagent for assaying tau protein in human plasma and feasibility study screening neurodegenerative diseases. Scientific Reports 2017 Aug 24;7(1):9304. doi:

 

• Lee CY, Sun Y, Lee HJ, Chen TF, Wang PN, Lin KN, Tang LY, Lin CC, Chiu MJ. Modest Overweight and Healthy Dietary Habits Reduce Risk of Dementia: A Nationwide Survey in Taiwan.  J Prev Alzheimers Dis. 2017;4(1):37-43.

 

• Lue LF, Sabbagh MN, Chiu MJ, Jing N, Snyder NL, Schmitz C, Guerra A, Belden CM, Chen TF, Yang CC, Yang SY, Walker DG, Chen K, Reiman EM. Plasma Levels of A-beta 42 and Tau Identified Probable Alzheimer's Dementia: Findings in Two Cohorts. Front Aging Neurosci. 2017 Jul 24;9:226.                

 

饒敦兼任助理教授(Jao Tun)

• T. Jao, M. Schröter, C.-L. Chen, Y.-F. Cheng, C.-Y. Z. Lo, K.-H. Chou, A. X. Patel, W.-C. Lin, C.-P. Lin, E. T. Bullmore, Functional brain network changes associated with clinical and biochemical measures of the severity of hepatic encephalopathy. NeuroImage 122, 332-344 (2015).

 

• T. Jao, C.-W. Li, P. E. Vértes, C. W. Wu, S. Achard, C.-H. Hsieh, C.-H. Liou, J.-H. Chen, E. T. Bullmore, Large-scale functional brain network reorganization during Taoist meditation. Brain connectivity,  (2015).

 

葉馨喬臨床助理教授

• Chen CH; Tang SC; Tsai LK; Yeh SJ; Chen KH; Li CH; Hsiao YJ; Chen YW, Yip BS; Jeng JS. Proteinuria independently predicts unfavorable outcome of ischemic stroke patients receiving intravenous thrombolysis. PLoS One 2013 Nov 22;8(11):e80527.

 

• Tang SC; Yeh SJ; Li YI; Wang YC; Baik SH; Santro T; Widiapradja A; Manzanero S; Sobey CG; Jo DG; Arumugam TV; Jeng JS. Evidence for a detrimental role of TLR8 in ischemic stroke. Exp Neurol 2013 Dec;250:341-347.

 

• Wu MC; Tsai LK; Wu CC; Yeh SJ; Tang SC; Chen YJ; Chen CL; Jeng JS. Thrombolytic Therapy Is an Only Determinant Factor for Stroke Evolution in Large Anterior Choroidal Artery Infarcts. J Stroke Cerebrovasc Dis. 2013 Oct 14. doi: 10.1016/j.jstrokecerebrovasdis.2013.09.015. [Epub ahead of print]

 

• Chen PK; Chiu PY; Tsai IJ; Tseng HP; Chen JR; Yeh SJ;, Yeh SJ; Sheu JJ; Chung CP; Wu MH; Hu CJ; Chang CY; Wei CY; Yip PK; Sung SF; Wang SJ; Hsu CY; Taiwan Stroke Registry Investigators. Onset headache predicts good outcome in patients with first-ever ischemic stroke. Stroke 2013 Jul;44(7):1852-1858.

 

• Yeh SJ, Tang SC, Tsai LK, Jeng JS. (2014) Pathogenetical Subtypes of Recurrent Intracerebral Hemorrhage: Designations by SMASH-U Classification System. Stroke. DOI: 10.1161/STROKEAHA.114.005598.

 

• Yeh SJ, Tsai LK, Tang SC, Jeng JS. (2014) Pin-point Pupils with Drowsiness as a Presentation of Hashimoto's Encephalopathy Mimicking Pontine Infarction. Acta Neurol Taiwan. Mar;23(1):19-23.

 

• Wu MC, Tsai LK, Wu CC, Yeh SJ, Tang SC, Chen YJ, Chen CL, Jeng JS. (2014) Thrombolytic Therapy Is an Only Determinant Factor for Stroke Evolution in Large Anterior Choroidal Artery Infarcts. J Stroke Cerebrovasc Dis. DOI: 10.1016/j.jstrokecerebrovasdis.2013.09.015.

 

• Chen CH, Tang SC, Tsai LK, Hsieh MJ, Yeh SJ, Huang KY, Jeng JS. (2014) Stroke code improves intravenous thrombolysis administration in acute ischemic stroke. PLoS One. DOI: 10.1371/journal.pone.0104862

 

• Tang SC, Yeh SJ, Tsai LK, Hu CJ, Lien LM, Peng GS, Yang WS, Chiou HY, Jeng JS. (2014) Association between plasma levels of hyaluronic acid and functional outcome in acute stroke patients. J Neuroinflammation. DOI: 10.1186/1742-2094-11-101.

 

• Lin SY, Tang SC, Tsai LK, Yeh SJ, Hsiao YJ, Chen YW, Chen KH, Yip BS, Shen LJ, Wu FL, Jeng JS. (2014) Orolingual angioedema after alteplase therapy of acute ischaemic stroke: incidence and risk of prior angiotensin-converting enzyme inhibitor use. Eur J Neurol. DOI: 10.1111/ene.12472

 

• Yeh SJ, Tang SC, Tsai LK, Lee CW, Chen YF, Liu HM, Yang SH, Kuo MF, Jeng JS. (2017) Color Doppler ultrasonography as an alternative tool for postoperative evaluation of collaterals after indirect revascularization surgery in Moyamoya disease. PLoS One. doi: 10.1371/journal.pone.0188948.