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Research and Development

There are 12 ongoing research projects shared by 7 physicians. Besides, our physicians are actively participated in attending the international or national conferences to share our experiences with the experts worldwide.

Here is the list of presentation of research papers in 2009:

  1. Tzen KY, Lee W, Hwu W, Wu RM. Using FDOPA PET and TRODAT-1 SPECT in selecting patients with aromatic L-amino acid decarboxylase (AADC) deficiency for gene therapy. J Nucl Med. 2009;50(S2):67P. Presented in Society of Nuclear Medicine 56th SNM Annual Meeting.  Toronto, Canada. June 13-17, 2009.
  2. Tzen KY, Lu M, Chang H, Hsu W. Two year experience of follow up of neuroblastic tumors using FDOPA PET. J Nucl Med. 2009;50(S2):270P. Presented in Society of Nuclear Medicine 56th SNM Annual Meeting.  Toronto, Canada. June 13-17, 2009.
  3. European Association of Nuclear Medicine: Clinical impact of 18F-FDG PET on the management of patients with early non-small-cell lung cancer by conventional workup.
  4. Wu YW, Yang WS, Kao HL, Huang PJ. Early Plaque Regression After 12-week Atorvastatin Treatment: Serial Evaluation by 18F-FDG PET/CT. The 10th US-Japan-Asia Dialogue on Cardiovascular Diseases and Young Investigator Competition (Best Poster Award) Tokyo, Japan, Aug. 22, 2009.
  5. Cheng MF, Wang HP, Wu YW. Value of whole body FDG PET/CT in indeterminate infiltrative hepatic tumors in an endemic area of viral hepatitis. SNM 56th Annual Meeting; Toronto, Canada, June 15, 2009.
  6.  Wu YW, Lee CM, Jui HY, Wang SS, Tzen KY. Myocardial perfusion reserve by positron emission tomography inversely correlates with intravascular ultrasound in angiographically normal cardiac transplant recipients. SNM 56th Annual Meeting; Toronto, Canada, June 15, 2009.
  7. Wu YW, Yang WS, Kao HL, Huang PJ, Chen MF. Reversal of vascular inflammation by 12-week atorvastatin. American Heart Association Scientific Sessions in Orlando, Florida, USA; November 17, 2009.
  8. Society of Nuclear Medicine 56th 2009 June 13-17th Annual Meeting, Toronto, Canada. Value of FDG PET/CT in indeterminate infiltrative hepatic tumors in an endemic area of viral hepatitis.
  9. Taiwanese Society of Nuclear Medicine: Tc-99m MDP Bone Scintigraphy False Negative but F-18 Fluoride PET True Positive for Metastatic Bone Lesion from Hepatocellular Carcinoma.
  10. Taiwanese Society of Nuclear Medicine: The diagnostic effectiveness of 99mTc-Sestamibi SPECT/CT in Primary Hyperparathyroidism.
  11. Taiwanese Society of Nuclear Medicine : 18F-FDG PET Findings in Sestamibi SPECT/CT in Alzheimer Dementia: An SPM Analysis.

 

In 2009, there were 19 published papers by our physicians in the SCI journals.

  1. Lee WT, Weng WC, Peng SF, Tzen KY. Neuroimaging findings in children with paediatric neurotransmitter diseases. J Inherit Metab Dis. 2009 Jun;32(3):361-70.
  2. Hsu WC, Tzen KY, Huy PT, Duet M, Yeh TH. An animal model of central auditory pathway imaging in the rat brain by high resolution small animal positron emission tomography. Acta Otolaryngol. 2009 Apr;129(4):423-8.
  3. Lee MJ, Mata IF, Lin CH, Tzen KY, Lincoln SJ, Bounds R, Lockhart PJ, Hulihan MM, Farrer MJ, Wu RM. Genotype-phenotype correlates in Taiwanese patients with early-onset recessive parkinsonism. Mov Disord. 2009 Jan 15;24(1):104-8.
  4. Wang LY, Wu MZ, Yen RF, Tzen KY. Asymptomatic thymic carcinoma with solitary hepatic metastasis detected by fluorodeoxyglucose positron emission tomography. J Formos Med Assoc. 2009;108:677-680.
  5. Yen RF, Wu VC, Liu KL, Cheng MF, Wu YW, Chueh SC, Lin WC, Wu KD, Tzen KY, Lu CC; TAIPAI Study Group. 131I-6beta-iodomethyl-19-norcholesterol SPECT/CT for primary aldosteronism patients with inconclusive adrenal venous sampling and CT results. J Nucl Med. 2009;50:1631-1637.
  6. Kuo SH, Yen RF, Lin CW, Chen LT, Tien HF, Cheng AL. Unusual presentation of multiple pathologic bone fractures in a patient with gastric mucosa-associated lymphoid tissue lymphoma. Ann Hematol. 2009, In press.
  7. TAIPAI Study Group, Wu VC, Chueh SC, Chang HW, Lin LY, Liu KL, Lin YH, Ho YL, Lin WC, Wang SM, Huang KH, Hung KY, Kao TW, Lin SL, Yen RF, Chen YM, Hsieh BS, Wu KD. Association of kidney function with residual hypertension after treatment of aldosterone-producing adenoma. Am J Kidney Dis. 2009;54:665-673.
  8. Tai CH, Yen RF, Lin CH, Yen KY, Yip PK, Wu RM, Lee MJ. Focal brain glucose hypermetabolism in myoclonus-dystonia syndrome caused by an epsilon-sarcoglycan gene mutation. Parkinsonism Relat Disord. 2009;15:614-616.
  9. Huang CT, Yen RF, Cheng MF, Hsu YC, Wei PF, Tsai YJ, Tsai MF, Shih JY, Yang CH, Yang PC. Correlation of F-18 Fluorodeoxyglucose-positron emission tomography maximal standardized uptake value and EGFR mutations in advanced lung adenocarcinoma. Medical oncology.2009; In press.
  10. Yen RF, Ting LL, Cheng MF, Wu YW, Tzen KY, Hong RL. Usefulness of 201Tl SPECT/CT relative to 18F-FDG PET/CT in detecting recurrent skull base nasopharyngeal carcinoma. Head & Neck. 2009;31:717-724.
  11. Lu CC, Yen RF, Cheng MF, Lin LC. Abnormal myocardial perfusion imaging after percutaneous coronary intervention without obstructing lesion. Clin Nucl Med.2009; 34:38-39.
  12. Yen RF, Yen MF, Hong RL, Tzen KY, Chien CR, Chen TH. The cost-utility analysis of 18-fluoro-2-deoxyglucose positron emission tomography in the diagnosis of recurrent nasopharyngeal carcinoma. Acad Radiol.2009; 16:54-60.
  13. Hwang JJ, Yang WS, Chiang FT, Chen MF, Lin HJ, Huang PJ, Hsu SHJ, Lai SK, Wu YW. Increased matrix metalloproteinase-1 concentrations are associated with advanced coronary artery disease. Atherosclerosis. 2009 May; 204(1): 293-7.
  14. Chang LC, Huang KC, Wu YW, Kao HL, Chen CL, Lai LP, Hwang JJ, Yang WS. The clinical implications of blood adiponectin in cardiometabolic disorders. J Formos Med Assoc. 2009 May; 108(5): 353-66.
  15. Li WY, Cheng MF, Chiu FC, Wu YW. Unusual finding of thoracic kidney in myocardial perfusion imaging by using SPECT/CT. Clin Nucl Med. 2009 Jun; 34(6): 379-80.
  16. Lee BC, Hsu HC, Tseng WY, Su MY, Chen SY, Wu YW, Chien KL, Chen MF. Effect of cardiac rehabilitation on angiogenic cytokines in postinfarction patients. Heart. 2009 Jun; 95(12): 1012-8.
  17. Lin HJ, Chao CL, Chien KL, Ho YL, Lee CM, Lin YH, Wu YW, Hsu RB, Chou NK, Wang SS, Chen CY, Chen MF. Elevated blood urea nitrogen-to-creatinine ratio increased the risk of hospitalization and all-cause death in patients with chronic heart failure. Clin Res Cardiol. 2009 Aug; 98(8): 487-92.
  18. Lin YH, Lin LY, Wu YW, Chien KL, Lee CM, Hsu RB, Chao CL, Wang SS, Hsein YC, Liah LC, Ho YL, Chen MF. The relationship between serum galectin-3 and serum markers of cardiac extracellular matrix turnover in heart failure patients. Clin Chim Acta. 2009 Nov; 409(1-2): 96-9.
  19. Cheng MF, Lin YH, Tseng WYI, Wu YW. Myocardial infarction without coronary artery stenosis illustrated by Tc-99m pyrophosphate scan, cardiac magnetic resonance imaging, and myocardial perfusion scintigraphy. Clin Nucl Med 2009;34:734-6.

 

In 2010

(A)SCI paper published

  1. Lee CF, Li GJ, Wan SY, Lee WJ, Tzen KY, Chen CH, Song YL, Chou YF, Chen YS, Liu TC. Registration of micro-computed tomography and histological images of the guinea pig cochlea to construct an ear model using an iterative closest point algorithm. Ann Biomed Eng. 2010 May;38(5):1719-27.(SCI)
  2. Cheng MF, Wu YW, Liu KL, Tang SC. Cerebral perfusion changes in migratory hemiplegic migraine: illustrated by Tc-99m ECD brain perfusion scan. Clin Nucl Med 2010 Jun;35:456-8.(SCI)
  3. Wu YW, Chen YH, Wang SS, Jui HY, Yen RF, Tzen KY, Chen MF, Lee CM. PET assessment of myocardial perfusion reserve inversely correlates with intravascular ultrasound findings in angiographically normal cardiac transplant recipients. J Nucl Med. 2010 Jun;51(6):906-12.(SCI)
  4. Yen RF, Chen CY, Cheng MF, Wu YW, Shiau YC, Wu K, Hong RL, Yu CJ, Wang KL, Yang RS. The diagnostic and prognostic effectiveness of F-18 sodium fluoride PET-CT in detecting bone metastases for hepatocellular carcinoma patients. Nucl MedCommun. 2010 Jul;31:637-645. (SCI)
  5. Lin CJ, Tai Y, Huang MT, Tsai YF, Hsu HJ, Tzen KY*, Liou HH. Cellular localization of the organic cation transporters, OCT1 and OCT2, in brain microvessel endothelial cells and its implication for MPTP transport across the blood-brain barrier and MPTP-induced dopaminergic toxicity in rodents. J Neurochem. 2010 Aug;114:717-727.(SCI)
  6. Lin YH, Lin C, Lo MT, Lin HJ, Wu YW, Hsu RB, Chao CL, Hsu HC, Wang PC, Wu VC, Wang SS, Lee CM, Chien KL, Ho YL, Chen MF, Peng CK. The relationship between aminoterminal propeptide of type III procollagen and heart rate variability parameters in heart failure patients: a potential serum marker to evaluate cardiac autonomic control and sudden cardiac death. Clin Chem Lab Med. 2010 Dec; 48(12): 1821-7.

 

(B)Conference presentation

  1. Yen TC, Kao PF, Cheng CY, Yen RF, Chiu NT. HIFU in BBB Opening for Drug Delivery. Presented in the 13th Asian Oceanian Congress of Radiology. Taipei, Taiwan. March 20-23, 2010.
  2. Tzen KY. Multiple-agent PET scans in the Era of Molecular Imaging. Presented in 5th Conference of International Medical Imaging and Radiological Sciences 2010. May 29, 2010.
  3. Tzen KY, Lu MY, Chang HH, Hsu WM, Luo TY, Shen LH. 18F-FDOPA PET scan is still useful in the presence of 123I-MIBG and 18F-FDG for neuroblastoma imaging. J Nucl Med. 2010;51(S2):1658. Presented in Society of Nuclear Medicine 57th SNM Annual Meeting.  Salt Lake City, USA. June 5-9, 2010.
  4. Leu SC, Tzen KY. Demonstrating different molecular components in neuroblastoma using 18F-FDOPA PET-18F-FDG PET coregistration with color coding. J Nucl Med. 2010;51(S2):1659. Presented in Society of Nuclear Medicine 57th SNM Annual Meeting.  Salt Lake City, USA. June 5-9, 2010.
  5. Shih IH, Mourtada F, Oh C, Chanda M, Tzen KY and Yang D. Development of IR-based automated module for synthesis of molecular imaging probes of neuroendocrine diseases. J Nucl Med. 2010;51(S2):1470. Presented in Society of Nuclear Medicine 57th SNM Annual Meeting.  Salt Lake City, USA. June 5-9, 2010.
  6. Tzen KY, Lu MY, Chang HH and Hsu WM. Molecular imaging with 18F-FDOPA PET in the early detection of new metastatic neuroblastoma in bone marrow. Presented in Advances in Neuroblastoma Research 2010. Stockholm, Sweden. June 21-24, 2010.
  7. Tzen KY, Lu MY, Chang HH, Lin KH, Jou ST, Yang YL, Lin DT and Hsu WM. Characterization of neuroblastoma imaging studies using F-18-DOPA PET/CT. Presented in Advances in Neuroblastoma Research 2010. Stockholm, Sweden. June 21-24, 2010.
  8. Liu YL, Hsu WM, Chang HH, Lin DT, Lin KH, Jou ST, Lu MY, Yang YL, Tzen KY, Peng SHF, Huang SF, Lee YL. The impact of a multidisciplinary team approach in the case management of neuroblastoma. Presented in Advances in NeuroblastomaResearch 2010. Stockholm, Sweden. June 21-24, 2010.
  9. Lu C, Yen R, Wu V, Wu K. The Quantification of I-131 6β-iodomethyl-19- norcholesterol SPECT/CT in detecting adrenal adenoma for patients with primary aldosteronism. Eur J Nucl Med Mol Imaging. 2010;37(S2):S204. Presented in Annual Congress of the European Association of Nuclear Medicine, Vienna, Austria. October 9-13, 2010.
  10. R. Yen, Yu C, Tzen K, Shiue C. The Diagnostic Usefulness of 18F-FDG and 18F-FLT PET in Pulmonary Lesions. Eur J Nucl Med Mol Imaging. 2010;37(S2):S319. Presented in Annual Congress of the European Association of Nuclear Medicine, Vienna,Austria. October 9-13, 2010.
  11. Wu YW, Lee CM, Wang SS, Wu CC. Usefulness of magnetocardiography in detecting cardiac allograft vasculopathy: correlation with intravascular ultrasound. Presented in the 3rd Asian Symposium on Magnetocardiography. Tsukuba, Japan. Dec 9-10, 2010.

 

In 2011

(A)SCI paper published

  1. Wang SY, Wu YW, Hsiao CH, Li MF, Hsu PY, Yen RF. F-18 FDG PET Images for subcutaneous panniculitis-like T-cell lymphoma. Clin Nucl Med. 2011 Jan; 36(1): 66-9.
  2. Wang SY, Cheng MF, Hwang JJ, Hung CS, Wu YW. Sex-specific normal limits of left ventricular ejection fraction and volumes estimated by gated myocardial perfusion imaging in adult patients in Taiwan: a comparison between two quantitative methods. Nucl Med Commun. 2011 Feb; 32(2): 113-20.
  3. Wang J, Shih TT, Yen RF, Lu YS, Chen CY, Mao TL, Lin CH, Kuo WH, Tsai YS, Chang KJ, Chien KL. The Association of Infrared Imaging Findings of the Breast with Hormone Receptor and Human Epidermal Growth Factor Receptor 2 Status of Breast Cancer. Acad Radiol. 2011 Feb;18:212-219.
  4. Wang CP, Shiau YC, Yen RF. F-18 FDG uptake in papillary carcinoma arising from thyroglossal duct cyst. Clin Nucl Med. 2011 Feb;36:141-142.
  5. Wu YW, Kao HL, Huang CL, Chen MF, Lin LY, Wang YC, Lin YH, Lin HJ, Tzen KY, Yen RF, Chi YC, Huang PJ, Yang WS. The effects of 3-month atorvastatin therapy on arterial inflammation, calcification, abdominal adipose tissue and circulating biomarkers. Eur J Nucl Med Mol Imaging. 2012 Mar; 39(3): 399-407.
  6. Hsieh TC, Wu YC, Sun SS, Yang CF, Yen KY, Liang JA, Kao CH. Rare breast and adrenal gland metastases from small-cell neuroendocrine carcinoma of uterine cervix. Clin Nucl Med. 2012 Mar; 37(3):280-3.
  7. Cheng MF, Huang JY, Han DY, Hsu PY, Yen RF. Gallium-67 SPECT/CT for Abdominal Abscess. Clinical Nuclear Medicine. 2011 Mar;36(3):258-60.
  8. Lin YH, Huang KH, Lee JK, Wang SM, Yen RF, Wu VC, Chung SD, Liu KL, Chueh SC, Lin LY, Ho YL, Chen MF, Wu KD. Factors influencing left ventricular mass regression in patients with primary aldosteronism post adrenalectomy. J Renin AngiotensinAldosterone Syst. 2011 Mar;12:48-53.
  9. Hung YL, Chen PC, Jeng SF, Hsieh CJ, Pen SS, Yen RF, Chou HC, Chen CY, Tsao PN, Hsieh WS. Serial measurements of serum alkaline phosphatase for early prediction of osteopaenia in preterm infants. J Paediatr Child Health. 2011 Mar;47:134-139.
  10. Chang L, Cheng MF, Kao YH, Chang CH, Wu YW. The role of lymphosintigraphy in diagnosis and monitor the response of physiotherapeutic technique in congenital lymphedema. Clin Nucl Med. 2011 Apr; 36(4): e11-2.
  11. Huang JY, Lu CC, Hsiao CH, Tzen KY. FDG PET-CT Findings in purely cutaneous Rosai-Dorfman disease. Clin Nucl Med 2011;Apr;36(4):e13-5.
  12. Cheng MF, Wu YW, Liu KL, Yen RF, Wu YM, Hsu C, Chang YT, Tzen KY, Wang HP. Diagnostic value of 18F-FDG-PET/CT in indeterminate infiltrative hepatic lesions in an endemic area of viral hepatitis. Nucl Med Commun. 2011 Apr;32(4):252-9.
  13. Tsao N, Wang CH, Her LJ, Tzen KY, Chen JY, Yu DF, Yang DJ. Development of 68Ga-glycopeptide as an imaging probe for tumor angiogenesis. J Biomed Biotechnol. 2011;2011:267206. Epub 2011 Apr 7.
  14. Su MY, Lee BC, Yu HY, Wu YW, Chu WC, Tseng WY. Exercise training increases myocardial perfusion in residual viable myocardium within infarct zone. J Magn Reson Imaging. 2011 Jul; 34(1): 60-8.
  15. Lin YH, Wang SM, Wu VC, Lee JK, Kuo CC, Yen RF, Liu KL, Huang KH, Chueh SC, Wang WJ, Lin LY, Chien KL, Ho YL, Chen MF, Wu KD; the TAIPAI study group. The association of serum potassium level with left ventricular mass in patients with primary aldosteronism. Eur J Clin Invest. 2011 Jul;41:743-750.
  16.  Wu VC, Yang SY, Lin JW, Cheng BW, Kuo CC, Tsai CT, Chu TS, Huang KH, Wang SM, Lin YH, Chiang CK, Chang HW, Lin CY, Lin LY, Chiu JS, Hu FC, Chueh SC, Ho YL, Liu KL, Lin SL, Yen RF, Wu KD; on behalf of the TAIPAI Study Group. Kidney impairment in primary aldosteronism. Clin Chim Acta. 2011 Jul;412:1319-1325.
  17. Kuo CC, Wu VC, Tsai CW, Huang KH, Wang SM, Li BC, Chang CC, Lu CC, Yang WS, Chao CT, Tsai IC, Lai CF, Lin WC, Wu MS, Lin YH, Lin CY, Chang HW, Wang WJ, Chiang WC, Kao TW, Chueh SC, Chu TS, Tsai TJ, Wu KD; TAIPAI Study Group. Combining body mass index and serum potassium to urine potassium clearance ratio is an alternative method to predict primary aldosteronism. Clin Chim Acta. 2011 Aug 17;412(17-18):1637-42
  18. Huang JY, Peng SF, Yang CC, Yen KY, Tzen KY, Yen RF. Neuroimaging findings in a brain with Niemann-Pick type C disease. J Formos Med Assoc. 2011 Aug;110(8):537-42.
  19. Huang CL, Wu YW, Wang SS, Tseng CD, Chiang FT, Hsu KL, Lee CM, Tzen KY. Continuous intravenous infusion of prostaglandin E1 improves myocardial perfusion reserve in patients with ischemic heart disease assessed by positron emission tomography: a pilot study. Ann Nucl Med. 2011 Aug;25(7):462-8.
  20. Kuo CC, Wu VC, Huang KH, Wang SM, Chang CC, Lu CC, Yang WS, Tsai CW, Lai CF, Lee TY, Lin WC, Wu MS, Lin YH, Chu TS, Lin CY, Chang HW, Wang WJ, Kao TW, Chueh SC, Wu KD, Taipai Study Group. Verification and evaluation of aldosteronism demographics in the Taiwan Primary Aldosteronism Investigation Group (TAIPAI Group). J Renin Angiotensin Aldosterone Syst. 2011 Sep;12(3):348-57.
  21. Lin MS, Chiu MJ, Wu YW, Huang CC, Chao CC, Chen YH, Lin HJ, Li HY, Chen YF, LC, Liu YB, Chao CL, Tseng WYI, Chen MF, Kao HL. Neurocognitive improvement after carotid stenting in patients with chronic internal carotid artery occlusion and cerebral ischemia. Stroke. 2011 Oct; 42(10): 2850-4
  22. Huang CL, Wu YW, Hwang CL, Jong YS, Chao CL, Chen WJ, Wu YT, Yang WS. The usefulness of infrared thermography in evaluation of patients at high risk for lower extremity peripheral arterial disease. J Vasc Surg. 2011 Oct; 54(4): 1074-80.
  23. Hsieh TC, Wu YC, Sun SS, Chiang IP, Yang CF, Yen KY, Kao CH. Synchronous squamous cell carcinomas of the esophagus and renal pelvis. Clin Nucl Med. 2011 Nov; 36(11):e171-4.
  24. Hsieh TC, Wu YC, Hsu CN, Yang CF, Yen KY, Kao CH, Sun SS. Lower neck neurilemmoma can masquerade as lymph node metastasis on FDG PET/CT in patient with nasopharyngeal carcinoma. Clin Nucl Med. 2011 Dec; 36(12):e217-9.
  25. Chien CL, Lee CM, Wu YW, Wu YT. Home-based exercise improves the quality of life and physical function but not psychological status of people with chronic heart failure: a randomised trial. J Physiotherapy. 2011; 57(3): 157-63.
  26. Chien CL, Wu YW, Yang WS, Yang PC, Su HM, Wu YT. Myocardial perfusion image in asymptomatic postmenopausal women with physical inactivity and overweight. Obesity Facts. 2011; 4(5): 371-8.

 

(B)Conference presentation

  1. Tzen KY, Chen CH, Shiue CY, Sheu JC . Clinical efficacy of combined 18F-Fluorocholine and 18F-FDG PET/CT in the diagnosis of hepatocellular carcinoma. J Nucl Med Meeting Abstracts 2011;52:313. Presented in Society of Nuclear Medicine 58th SNM Annual Meeting. San Antonio, Texas, USA. June 4-8, 2011.
  2. Tzen KY. Molecular Imaging in Neuroblastoma using Multi-Nuclear Probes. Presented in the Terry Fox Research Institute ?National Science Council Taiwan Cancer Research Symposium, Taipei, Taiwan. Dec. 6, 2011.
  3. Yen RF, Yu HJ, Pu YS, Cheng CH, Liang PC. The diagnostic usefulness of 18F-Fluorocholine Positron Emission Tomography in Recurrent/Metastatic Prostate cancer. EANM'11 - Annual Congress of the European Association of Nuclear Medicine. Birmingham, United Kingdom. October 15-19, 2011.
  4. Lu CC, Yu HJ, Pu YS, Cheng CH, Liang PC, Yen RF. The influence of hormone therapy in 18F-Fluorocholine PET in prostate cancer. EANM'11 - Annual Congress of the European Association of Nuclear Medicine, 2011 Oct, Birmingham, United Kingdom. October 15-19, 2011.
  5. Wu YW, Lin MS, Wu WC, Kao HL. Improvement In Cerebral Glucose Metabolism in Patients with Symptomatic Carotid Artery Occlusion or Severe Stenosis after Stenting: A PET Study. XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET. Barcelona, Spain, May 24-28, 2011
  6. Liu YL, Tzen KY, Hsu WM, Jou ST, Lu MY, Yang YL, Chang HH, Lee H, Lin DT, Lin KH. Neuroblastic tumors (NTs) with high 18F-FDOPA avidity will show higher aromatic amino acid decarboxylase expression. J Nucl Med Meeting Abstracts 2011;52:402. Presented in Society of Nuclear Medicine 58th SNM Annual Meeting. San Antonio, Texas, USA. June 4-8, 2011.
  7. Kuo SH, Cheng MF, Wu YW, Liao WC, Wang HP. Serum IgG4 level correlates with extra-pancreatic involvement on fluorodeoxyglucose positron emission tomography in autoimmune pancreatitis. Joint meeting of the 4th Asian-Oceanic Pancreas Association and 2011 Annual Congress of the Korean Pancreatobiliary Association; Jeju, Korea. September 2-3, 2011.

 

In 2012

(A)SCI paper published

  1. MY Lu, YL Liu, HH Chang, ST Jou, YL Yang, KH Lin, DT Lin, YL Lee, Hsinyu Lee, Pei-Yi Wu, TY Luo, LH Shen, SF Huang, YF Liao, WM Hsu, KY Tzen*. Characterization of Neuroblastic Tumors Using 18F-FDOPA PET. J Nucl Med. Accepted 2012 July 27.
  2. Cheng MF, Huang JJ, Chen JS, Yu SC, Yen RF, Tzen KY, Wu YW. Atypical thymic carcinoid associated with coronary artery spasm: Incidental finding of myocardial perfusion imaging. Int J Cardiol. 2012 Apr 20. [Epub ahead of print]
  3. Lu YS, Chou CH, Tzen KY, Gao M, Cheng AL, Kulp SK, Cheng JC. Radiosensitizing effect of a phenylbutyrate-derived histone deacetylase inhibitor in hepatocellular carcinoma. Int J Radiat Oncol Biol Phys. 2012 Jun 1;83(2):e181-9.
  4. Hwu WL, Muramatsu S, Tseng SH, Tzen KY, Lee NC, Chien YH, Snyder RO, Byrne BJ, Tai CH, Wu RM. Gene therapy for aromatic L-amino acid decarboxylase deficiency. Sci Transl Med. 2012 May 16;4(134):134ra61.
  5. Han DY, Cheng MF, Yen RF, Tzen KY, Wu YW. Postoperative lymphocele demonstrated by lymphoscintigraphy SPECT/CT. Clin Nucl Med. 2012 Apr;37(4):374-6.
  6. Ono Y, Lin HC, Tzen KY, Chen HH, Yang PF, Lai WS, Chen JH, Onozuka M, Yen CT. Active coping with stress suppresses glucose metabolism in the rat hypothalamus. Stress. 2012 Mar;15(2):207-17.
  7. Wu YW, Kao HL, Huang CL, Chen MF, Lin LY, Wang YC, Lin YH, Lin HJ, Tzen KY, Yen RF, Chi YC, Huang PJ, Yang WS. The effects of 3-month atorvastatin therapy on arterial inflammation, calcification, abdominal adipose tissue and circulating biomarkers. Eur J Nucl Med Mol Imaging. 2012 Mar;39(3):399-407.
  8. Cheng MF, Lin MW, Wu CT, Shih SR, Wu YW, Tzen KY, Yen RF. Asymmetric intense bilateral adrenal uptake on [18F]fluorodeoxyglucose positron emission tomography/computed tomography in a patient with solitary pulmonary nodule. J Clin Oncol. 2012 Feb 20;30(6):e83-5.
  9. Chou CH, Teng CM, Tzen KY, Chang YC, Chen JH, Cheng JC. MMP-9 from sublethally irradiated tumor promotes Lewis lung carcinoma cell invasiveness and pulmonary metastasis. Oncogene. 2012 Jan 26;31(4):458-68.

(B)Conference presentation

  1. Tzen KY, Lu MY, Liu YL, Hsu WM. The complementary role of 18F-FDOPA and 18F-FDG PET scans in the follow up of neuroblastoma. Presented in Advances in Neuroblastoma Research 2012. Toronto, Canada. June 18-21, 2012.
  2. Tzen KY, Liu YL, Lu MY, Chang HH, Jou ST, Yang YL, Lin DT, Lin KH, Su YN, Hsu WM. FDG:FDOPA uptake ratio by PET scans at diagnosis correlates with genomic type and treatment outcome of neuroblastoma. Presented in Advances in Neuroblastoma Research 2012. Toronto, Canada. June 18-21, 2012.
  3. Ko CL, Wu YW, Cheng MF, Yen RF, and Tzen KY. Effects of respiration on myocardial perfusion imaging with a CZT SPECT camera. J Nucl Med Meeting Abstracts 2012;53:31. Presented in Society of Nuclear Medicine 59th SNM Annual Meeting. Miami,Florida, USA. June 9-13, 2012.
  4. KY Tzen, NC Lee, YD Shieh, YH Chien, PW Chen, WL Hwu, Molecular Imaging of a Murine Model for Aromatic L-Amino Acid Decarboxylase Deficiency, Presented in World Molecular Imaging Congress, Dublin, Ireland, Sep 5-8, 2012.
  5. KY Tzen, YL Liu, MY Lu, IS Yu, CN Chen, WM Hsu, Multiple PET Imaging Using 18F-FDG, 18F-FDOPA and 18F-FLT in a Genetically Engineered Mouse Model for neuroblastoma, Presented in World Molecular Imaging Congress, Dublin, Ireland, Sep 5-8, 2012.
  6. WC Hsu, KY Tzen, TH Yeh, PTB Huy, M Duet, The central cortical responses of 18F-FDG uptake in a rat model of central auditory pathway with rat voice stimulation by high resolution small animal positron emission tomography, Presented in World Molecular Imaging Congress, Dublin, Ireland, Sep 5-8,  2012.

 

In 2014

(A)SCI paper published

  1. Lu CC, Wu VC, Wu KD, Liu KL, Lin WC, Cheng MF, Tzen KY, Yen RF; TAIPAI Study Group. Prognostic value of semiquantification NP-59 SPECT/CT in primary aldosteronism patients after adrenalectomy. Eur J Nucl Med Mol Imaging. 2014 Jul;41(7):1375-84.
  2. Tzen KY, Yang SY, Chen TF, Cheng TW, Horng HE, Wen HP, Huang YY, Shiue CY, Chiu MJ. Plasma Aβ but not tau is related to brain PiB retention in early Alzheimer's disease. ACS Chem Neurosci. 2014 Sep 17;5(9):830-6.
  3. Ko CL, Wu YW, Cheng MF, Yen RF, Wu WC, Tzen KY. Data-driven respiratory motion tracking and compensation in CZT cameras: A comprehensive analysis of phantom and human images. J Nucl Cardiol. 2015 Apr;22(2):308-18.
  4. Liu CJ, Cheng JS, Lee JM, Cheng MF, Tzen KY, Yen RF. Patterns of Nodal Metastases on F18-FDG PET/CT in Patients with Esophageal Squamous Cell Carcinoma is Useful to Guide Treatment Planning of Radiotherapy. Clin Nucl Med (2014/12 accepted).

 

(B)Conference presentation

  1. Chi-Lun Ko, Ruoh-Fang Yen, Mei-Fang Cheng, Yen-Wen Wu, and Kai-Yuan Tzen. Combination of baseline 18F-FDG intratumor uptake heterogeneity indices derived from genetic algorithm predicts therapy response and survival in esophageal cancer. Society of Nuclear Medicine and Molecular Imaging Annual Meeting 2014, June 7-11, 2014, St. Louis, Missouri, USA. J Nucl Med Meeting Abstracts May 2014;55:73.
  2. Chi-Lun Ko, Yen-Wen Wu, Mei-Fang Cheng, Ruoh-Fang Yen, and Kai-Yuan Tzen. Dual-motion frozen reconstruction technique improves the diagnostic accuracy of myocardial perfusion SPECT imaging in CZT cameras. Society of Nuclear Medicine and Molecular Imaging Annual Meeting 2014, June 7-11, 2014, St. Louis, Missouri, USA. J Nucl Med Meeting Abstracts May 2014;55:237.
  3. Ya-Yao Huang, Chia-Ling Tsai, Kai-Yuan Tzen, and Chyng-Yann Shiue. Revisiting the nucleophilic radiosynthesis of [18F] FDGal using talose triflate: A comparison with [18F]FDG. Society of Nuclear Medicine and Molecular Imaging Annual Meeting 2014, June 7-11, 2014, St. Louis, Missouri, USA. J Nucl Med Meeting Abstracts May 2014;55:1036.
  4. Ya-Yao Huang, Ching-Hung Chiu, Pei-Yao Lin, Chi-Han Wu, Chung-Hsien Ho, Hung-Man Yu, Mei-Hui Wang, Wuu-Jyh Lin, Kai-Yuan Tzen, and Chyng-Yann Shiue. Evaluation of 5-[18F]fluoro-2��-deoxycytidine as a tumor imaging agent: A comparison with 5-[18F]fluoro-2��-deoxyuridine. Society of Nuclear Medicine and Molecular Imaging Annual Meeting 2014, June 7-11, 2014, St. Louis, Missouri, USA. J Nucl Med Meeting Abstracts May 2014;55:1077.
  5. Ya-Yao Huang, Pei-Yao Lin, Hsin-Yi Shen, Zih-Rou Huang, Kai-Yuan Tzen, Ling-Wei Hsin, and Chyng-Yann Shiue. Evaluation of 18F-labeled MADAM analogs as potential SERT imaging agents: A comparison with 4-[18F]-ADAM. Society of Nuclear Medicine and Molecular Imaging Annual Meeting 2014, June 7-11, 2014, St. Louis, Missouri, USA. J Nucl Med Meeting Abstracts May 2014;55:1101.
  6. Kai-Yuan Tzen, Meei-Ling Jan, Yu-Ching Ni, Jia-Yi Yeh, and Chiun-Sheng Huang. Feasibility study of a new prototype positron emission mammography (PEM). Society of Nuclear Medicine and Molecular Imaging Annual Meeting 2014, June 7-11, 2014, St. Louis, Missouri, USA. J Nucl Med Meeting Abstracts May 2014;55:1539.
  7. Kuan-Yin Ko, Yen-Wen Wu, Mei-Fang Cheng, Ruoh-Fang Yen, and Kai-Yuan Tzen. The clinical significance of right ventricular activity on Tl-201 myocardial SPECT using CZT cameras. Society of Nuclear Medicine and Molecular Imaging Annual Meeting 2014, June 7-11, 2014, St. Louis, Missouri, USA. J Nucl Med Meeting Abstracts May 2014;55:1741.
  8. Chia-Ju Liu, Yen-Wen Wu, Mei-Fang Cheng, Ruoh-Fang Yen, and Kai-Yuan Tzen. Incremental diagnostic performance of combined parameters in the detection of severe coronary artery disease using exercise gated myocardial perfusion imaging. Society of Nuclear Medicine and Molecular Imaging Annual Meeting 2014, June 7-11, 2014, St. Louis, Missouri, USA. J Nucl Med Meeting Abstracts May 2014;55:1745.
  9. Chi-Lun Ko, Yen-Wen Wu, Mei-Fang Cheng, Ruoh-Fang Yen, and Kai-Yuan Tzen. Improved diagnostic accuracy of myocardial perfusion SPECT imaging in CZT cameras after transmissionless attenuation and scatter correction. Society of Nuclear Medicine and Molecular Imaging Annual Meeting 2014, June 7-11, 2014, St. Louis, Missouri, USA. J Nucl Med Meeting Abstracts May 2014;55:1779.
  10. Yen RF, Wang MH, Wu HL, Lin WZ, and Huang YH. Hepatic asialoglycoprotein receptor binding demonstrated by In-111 DTPA-hexa lactoside and Tc-99m TriGalNAc scintigraphies: A woodchuck model. World Molecular Imaging Congress 2014, September 17-20, Seoul, Korea.
  11. Ching-Chu Lu, Vin-Cent Wu, Kwan-Dun Wu, Kai-Yuan Tzen and Ruoh-Fang Yen. Semiquatification of Captopril Renal Scintigraphy in detection of Renal Artery Stenosis and its Prognostic Value. The Asian Regional Cooperative Council for Nuclear Medicine Annual Meeting, 11th-12th November 2014, Osaka, Japan.
  12. Huang Y-Y, Tsai C.-L., Tzen K-Y, Shiue C.-Y. Experimental and Theoretical Revisit of Nucleophilic Radiosynthesis of [18F]FDGal and [18F]FDG, 2014 European Symposium on Radiopharmacy and Radiopharmaceuticals, Pamplona, Spain, #PP45. Q J Nucl Med Mol Imag, 2014;58(Suppl 1):65.
  13. Ya-Yao Huang, Ching-Hong Chiu, Chih-Yuan Lin, Pei-Yao Lin, Chung-Hsien Ho, Hung-Wen Yu, Mei-Hui Wang, Wu-Jyh Lin, Kai-Yuan Tzen, Chyng-Yann Shiue, Evaluation of 5-[18F]Fluoro-2'-deoxycytidine as a Tumor Imaging Agent: A Comparison with 5-[18F]Fluoro-2'-deoxyuridine, 2014 Japan Taiwan Bilateral Conference on Biomedical and Plasmonic Imaging, Taiwan, 2014, #P11.
  14. Ya-Yao Huang, Pei-Yao Lin, Hsin-Yi Shen, H-Y, Zih-Rou Huang, Kai-Yuan Tzen, Lin-Wei Hsin, Chyng-Yann Shiue, Evaluation of 18F-labeled MADAM analogs as potential SERT imaging agents: A comparison with 4-[18F]-ADAM, 2014 Japan Taiwan Bilateral Conference on Biomedical and Plasmonic Imaging, Taiwan, 2014, #P12.
  15. Ya-Yao Huang, Chia-Ling Tsai, Kai-Yuan Tzen, Chyng-Yann Shiue, Revisiting the Nucleophilic Radiosynthesis of [18F]FDGal using Talose Triflate: A comparison with [18F]FDG, 2014 Japan Taiwan Bilateral Conference on Biomedical and PlasmonicImaging, Taiwan, 2014, #P13.