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歷史沿革

病理學為臨床醫學的基礎，也是醫學研究中極為重要的一門學問。台大醫學院病理學科的前身是台北帝國大學醫學部病理學教室，於1936年及1937年分別開設病理學第一及第二講堂，位置在舊址「綜合研究館」（目前醫學院二號館附近）。1954年，在附設醫院設立「病理科」，與病理學科及研究所成為一綜合基礎與臨床教學服務的特殊學科，研究得以拓展。1994年病理科改編為病理部，並依功能分設各科：解剖病理科、法醫病理科、分子病理科、細胞病理科及遺傳病理科。2000年將功能分科改為外科病理科、解剖及法醫病理科、細胞病理科及分子病理科，2008年正式成立四個分科：外科病理科、解剖及法醫病理科、細胞病理科及分子病理科。2010年解剖及法醫病理科更名為大體解剖病理科。至今已有60年歷史。

臨床服務

• 外科病理組織切片檢查
• 冷凍切片檢查
• 組織化學染色檢查
• 免疫組織化學染色檢查
• 免疫螢光染色檢查（包括直接與間接）
• 婦科細胞學檢查
• 細胞蠟塊
• 電子顯微鏡檢查
• 病理解剖
• 分子病理學檢查
• 血液病染色體檢查
• 院內病理資料庫檢索服務
• 教學研究用病理檢體組織庫
• 簽約醫院院外代檢服務

教學

• 本部提供完整的解剖病理專科醫師訓練計劃。住院醫師在第一、二年輪做外科檢體及病理解剖的病例，第二年下半年及第三年輪流接受腎臟病理、血液病理、細胞病理等各次專科訓練一至三個月。每週有五種討論會訓練所有的住院醫師，包括：臨床病理討論會、外科病理討論會、大體解剖及顯微切片討論會、血液病理討論會及每日晨會等。
• 對醫學系、牙醫學系四年級學生、護理系二年級、醫技系三年級、藥學系四年級以及公衛、復建、職能治療等各系之三年級同學的病理科課程及實習，由全體病理部教員及主治醫師負責擔任指導及上課。
• 本部主治醫師及教師每年均應院外邀請演講。
• 本科部另設有病理研究所，招收博士班及碩士班學生。

研究服務特點及發展方向

• 肝癌及鼻咽癌分子病理研究
• 維持優良的冷凍切片品質，並利用組織捺印抹片技術，快速並正確判讀結果，提供手術醫師參考。
• 淋巴瘤之致病機制研究與分子診斷
• 胸腔疾病之轉譯醫學研究
• 研發多重色彩螢光原位雜交技術，提供臨床醫師評估病人的預後及決定最適當的治療方式。
• 乳癌之細胞素及細胞接受體之研究
• 提供感染性疾病病因的病理診斷
• 配合癌症卓越研究計劃，拓展腫瘤分子病理診斷
• 承辦人體生物資料庫業務

近年來重大成果

• 本部獲衛生署國家型計畫基因體計畫支持，建立腫瘤組織資料庫，提供各科相關研究。所發展之組織庫，能應付將來微切技術需要，並能順利抽取RNA。
• 設立分子病理實驗室協助惡性腫瘤的基因診斷。分子病理實驗室利用各種先進分生方法來診斷疾病。例如：診斷基因重組、染色體病變之疾病，這些結果得以和傳統形態診斷，或免疫組織化學診斷整合。
• 將研究委託案件制度化，病理蠟塊整理專業化，提供各部研究及服務之支援。組織臘塊建立完善歸檔制度，並提供合適的標本，供基因分析。
• 一般切片染色自動化，易於品質管制。利用自動染色設備，提昇染色品質。
• 改善免疫組織化學實驗室，購入自動免疫染色機，除可快速診斷外，亦改進了人工染色技術無法控制的缺失。
• 嚴格執行品質管制，提昇診斷之準確度。運用Tissue committee的功能，確實結合病理醫師與臨床科醫師來促成外科病理的品質管制。

未來展望

1. 服務方面： 以病人為中心的服務方式，利用創新的方法增進病理報告的準確性及效率。
2. 研究及教學方面：

• 繼續癌症卓越研究計畫已有之成果，並運用癌症生物標記整合及服務中心之功能，拓展分子病理診斷(molecular pathology)。
• 培養次專科人才出國進修，與國外專家進行合作研究計畫，以期自我突破。

 

Department Profile

The Department of Ophthalmology became the third specialty department established by National Taiwan University Hospital in March 1897.

Serving a large number of patients on a daily basis, we offer a wide variety of specialized examination and treatment options while continuing to adopt the latest medical equipment and technology. We pride ourselves in maintaining excellent standards in ophthalmological care comparable to those of the best hospitals in the world. The department is functionally divided into the following seven specialties: Cornea, Retina, Pediatric Ophthalmology & Refraction, Oculoplasty, Neuro-Ophthalmology, Glaucoma, and Uveitis.

Below is an outline of the direction we have planned for the department. On the medical care front, we take an active approach in adopting the most advanced medical technology to improve the quality of care. In the area of academic development, the focus of our research is on domestic eye diseases and on innovative treatment methods, as well as on research at the levels of genomic medicine and molecular biology. As for the education of our medical students, apart from conventional classroom teaching, we also place an emphasis on clinical training and minimally invasive surgical procedures. Production of pedagogical videos also aids in our teaching efforts. For our resident physicians, we have adopted a step-by-step approach in our training programs, which include clinical diagnosis and treatment, surgical training and the development of medical research skills, with the objective of educating them to become the country’s top specialists in our field.

Going forward, the Department of Ophthalmology will continue to improve ourselves to achieve the best that we can be. In addition to contributing to society, we have set our sights on becoming one of the leading ophthalmology departments in the world.

 

Our Strengths

Based on the diverse needs of our patients and the categorization of eye diseases, the department takes an active approach in training subspecialists in various functional subdisciplines. In addition to receiving subspecialty training abroad, our physicians also participate regularly in domestic and international seminars to keep their clinical techniques and academic research at the highest and most advanced levels globally.

Our doctors in the Cornea Section have published many research papers in international journals on the diagnosis and treatment of corneal ulcers and excimer laser refractive surgeries. NTUH is the first hospital in Taiwan to have introduced excimer laser surgery for myopia correction. Since 1983, the Pediatric Ophthalmology and Refraction Section has conducted epidemiological investigations, over a number of periods totaling more than twenty years, on the refractive changes in Taiwanese schoolchildren. We have achieved outstanding results in the research of myopia-related genetics and medication, strabismus, amblyopia, and stereoscopic vision. The Glaucoma Section has made unique contributions to the treatment of closure glaucoma. The Oculoplasty Section has achieved remarkable progress in the diagnosis and treatment of thyroid eye diseases and orbital tumors. In addition to being innovative in surgical procedures for retinal detachment and chorioretinal vascular diseases, the Retina Section has achieved impressive results in the basic research of laser and drug treatment as well as cytokines.

The department holds weekly academic conferences conducted in the English language in order to enhance doctors’ communicative capabilities when delivering presentations to a wider audience in international symposiums. At daily morning meetings, case conferences are also carried out for various subspecialties.

 

Service Offerings

Cataract Treatment
We utilize surgical microscopes of the highest precision and the most advanced phacoemulsification equipment to develop mini-incision, suture-free cataract surgeries with foldable intraocular lenses. Nd:YAG laser can be used at the outpatient clinic’s laser center to treat after cataracts.

 

Photorefractive Correction Treatment 
We currently employ the most advanced wavefront technology to tailor laser treatments for individual patients to correct refractive problems and higher-order aberrations. Flying spot is used in conjunction with an iris recognition system and an eye tracker to enable speedy and precision surgeries. For the creation of corneal flaps, the latest femtosecond lasers are available as a treatment option in addition to microkeratomes.

The Department of Ophthalmology comprises seven subspecialty sections. We perform examinations, diagnoses, treatments and surgeries for various eye diseases.
 

Pediatric Ophthalmology and Refraction Section
This section provides ophthalmological care to children and adults.
Main categories:

We perform the following types of surgery:

Cornea Section
This section provides diagnoses and treatments for various corneal, scleral, conjunctival, and eyelid diseases. 
Main categories:

We perform the following types of surgery:

Glaucoma Section
This section provides diagnoses and treatments for adult and child glaucoma patients.
Main categories:

We perform the following types of surgery:

Retina Section
This section provides diagnoses and treatments for retinal, choroidal and vitreal diseases.
Main categories:

We perform the following types of surgery:

Oculoplasty Section
This section provides diagnoses and treatments for eyelid, orbital and neuro-ophthalmic diseases as well as performs ocular plastic surgeries.
Main categories:

Neuro-Ophthalmology Section
This section provides diagnoses and treatments for neuro-ophthalmic diseases.

Main categories:

Uveitis Section
This section provides diagnoses and treatments for uveitis.
Main categories: