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乳房醫學中心研究成果介紹

 

  • Shao, Z., Tseng, L.M., Huang, C.S., Pang, D., Yang, Y., Li, W., Liao, N., Geng, C., Zhang, Q., Xu, B., Liu, D., Kwong, A. & et al. Pertuzumab and trastuzumab as adjuvant treatment for HER2-positive early breast cancer: outcomes in Chinese patients in the APHINITY study. Japanese Journal of Clinical Oncology 51, 345-353 (2021).
  • Lin, C.H., Huang, R.Y., Lu, T.P., Kuo, K.T., Lo, K.Y., Chen, C.H., Chen, I.C., Lu, Y.S., Chuang, E.Y., Thiery, J.P., Huang, C.S. * & Cheng, A.L. High prevalence of APOA1/C3/A4/A5 alterations in luminal breast cancers among young women in East Asia. NPJ Breast Cancer 7, 88 (2021).
  • Huang, C.S., Yang, Y., Kwong, A., Chen, S.C., Tseng, L.M., Liu, M.C., Shen, K., Wang, S., Ng, T.Y., Feng, Y., Sun, G., Yan, I.R. & Shao, Z. Trastuzumab emtansine (T-DM1) versus trastuzumab in Chinese patients with residual invasive disease after neoadjuvant chemotherapy and HER2-targeted therapy for HER2-positive breast cancer in the phase 3 KATHERINE study. Breast Cancer Research and Treatment 187, 759-768 (2021).
  • H.J. Burstein, G. Curigliano, B. Thürlimann, W.P. Weber, P. Poortmans, M. Regan, H.J. Senn, E.P. Winer, M. Gnant, Panelists of the St.Gallen Consensus Conference .Customizing local and systemic therapies for women with early breast cancer: The St.Gallen International Consensus Guidelines for treatment of early breast cancer 2021. Annals of Oncology doi:10.1016 (2021)
  • Tsai, L.W., Lee, Y.H., Lo, C, Lien, H.C., Wang, M.Y., Jan, I.S., Yen, R.F., Hu, F.C., Huang, C.S. *, Factors predicting one or two sentinel lymph nodes to be accepted for sentinel lymph node biopsy alone after neoadjuvant therapy in initially node-positive breast cancer patients. Surgical Oncology 39 (2021)
  • Harbeck N, Rastogi P, Martin M, Tolaney SM, Shao ZM, Fasching PA,  Huang CS, et al. Adjuvant Abemaciclib Combined With Endocrine Therapy for High-Risk Early Breast Cancer: Updated Efficacy and Ki-67 Analysis From the monarchE Study. Annals of Oncology. Sep 29; S0923-7534 (21) 04494-X. (2021).
  • Lin, P.H., Wang, M.Y., Lo, C., Tsai, L.W., Yen, T.C., Huang, T.Y., Huang, W.C., Yang, K., Chen, C.K., Fan, S.C., Kuo,S.H., Huang, C.S. *Circulating Tumor DNA as a Predictive Marker of Recurrence for Patients With Stage II-III Breast Cancer Treated With Neoadjuvant Therapy. Frontiers in Oncology 11(2021).
  • Lin, L.C., Huang, K.C., Huang, C.S., Su, M.Y., Hung, C.L., Tu, Y.C., Hwang, J.J. Artificial Intelligence Aids Cardiac Image Quality Assessment for Improving Precision in Strain Measurements. JACC Journals (2020)
  • Lo C., Hsu YL., Cheng CN., Lin CH., Kuo HC., Huang CS*., Kuo CH*. Investigating the Association of the Biogenic Amine Profile in Urine with Therapeutic Response to Neoadjuvant Chemotherapy in Breast Cancer Patients. Journal of Proteome Research. 19(10):4061-4070 (2020).
  • Hurvitz, S.A., Martín, M., Press, M.F., Chan, D., Fernandez-Abad, M., Petru, E., Rostorfer, R., Guarneri, V., Huang, C.S., Barriga, S., Wijayawardana, S.R., Brahmachary, M., Ebert, P. J., Hossain, A., Liu, J., Abel, A., Aggarwal, A., Jansen, V.M., Slamon, D.J. Potent cell cycle inhibition and upregulation of immune response with abemaciclib and anastrozole in neoMONARCH, Phase 2 neoadjuvant study in HR+/HER2- breast cancer. Clinical Cancer Research 26(3), 566-580 (2020)
  • Chen, C.H., Lu, Y.S., Cheng, A.L., Huang, C.S., Kuo, W.H., Wang, M.Y., Chao, M., Chen, I.C., Kuo, C.W., Lu, T.P., Lin, C.H.. Disparity in Tumor Immune Microenvironment of Breast Cancer and Prognostic Impact: Asians versus Western Populations. The Oncologist 25(1), e16-e23 (2020)
  • Moon, W.K., Huang, Y.S., Hsu, C.H., Chang Chien, T.Y., Chang, J.M., Lee, S.H., Huang, C.S., Chang, R.F. Computer-aided tumor detection in automated breast ultrasound using a 3-D convolutional neural network. Computer Methods and Programs in Biomedicine 190, 105360 (2020)
  • Lin, P.H., Chen, M., Tsai, L.W., Lo, C., Yen, T.C., Huang, T.Y., Chen, C.K., Fan, S.C., Kuo, S.H., Huang, C.S.*. Using next generation sequencing to redefine BRCAness in triple-negative breast cancer. Cancer Science 2020 Jan 20. doi: 10.1111/cas.14313. [Epub ahead of print]
  • Conte, P., Schneeweiss, A., Loibl, S., Mamounas E.P., Minckwitz G., Mano M.S. Untch M., Huang, C.S., Wolmark N., Rastogi P., D’Hondt V., Redondo A., Stamatovic L., Bonnefoi H., Castro‐Salguero H., Fischer H.H., Wahl T., Song C.,  Boulet T., Trask P., Geyer Jr C.E. Patient‐reported outcomes from KATHERINE: A phase 3 study of adjuvant trastuzumab emtansine versus trastuzumab in patients with residual invasive disease after neoadjuvant therapy for human epidermal growth factor receptor 2–positive breast cancer. Cancer 126(13), 3132-3139 (2020)
  • Huang, C.S., Yu, A.L., Tseng, L.M., Chow, L.W.C., Hou, M.F., Hurvitz, S.A., Schwab, R.B., Murray, J.L., Chang, H.K., Chang, H.T., Chen, S.C., Kim, S.B., Hung, J.T., Ueng, S.H., Lee, S.H., Chen, C.C., Rugo, H.S. Globo H-KLH vaccine adagloxad simolenin (OBI-822)/OBI-821 in patients with metastatic breast cancer: phase II randomized, placebo-controlled study. Journal for ImmunoTherapy of Cancer e000342. doi:10.1136 (2020)
  • Dawood, S., Chiu, J.W.Y., Huang, C.S., Nag, S., Sookprasert, A., Yap, Y.S., Yusof, M.M. Palbociclib and beyond for the treatment of HR + HER2- metastatic breast cancer: an Asian-Pacific perspective and practical management guide on the use of CDK4/6 inhibitors. Current Medical
  • Hurvitz, S.A., Martin, M., Jung, K.H., Huang, C.S., Harbeck, N., Valero, V., Stroyakovskiy, D., Wildiers, H., Campone, M., Boileau, J.F., Fasching, P.A., Afenjar, K., Spera, G., Lopez-Valverde, V., Song, C., Trask, P., Boulet, T., Sparano, J.A., Symmans, W.F., Thompson, A.M., Slamon, D.. Neoadjuvant Trastuzumab Emtansine and Pertuzumab in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Three-Year Outcomes From the Phase III KRISTINE Study. Journal of Clinical Oncology 37(25), 2206-2216 (2019)
  • H.H., Jacot, W., Conlin, A.K., Arce-Salinas, C., Wapnir, I.L., Jackisch, C., DiGiovanna, M.P., Fasching, P.A., Crown, J.P., Wulfing, P., Shao, Z., Rota Caremoli, E., Wu, H., Lam, L.H., Tesarowski, D., Smitt, M., Douthwaite, H., Singel, S.M., Geyer, C.E., Jr. & Investigators, K. Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer. New England Journal of Medicine 380, 617-628 (2019).
  • Chiang, T.C., Huang, Y.S., Chen, R.T., Huang, C.S.* & Chang, R.F.* Tumor Detection in Automated Breast Ultrasound Using 3-D CNN and Prioritized Candidate Aggregation. IEEE Transactions on Medical Imaging 38(1), 240-249 (2019).
  • Chen, P.D., Hu, R.H., Liang, J.T., Huang, C.S. & Wu, Y.M..Toward a fully robotic surgery: Performing robotic major liver resection with no table-side surgeon. The International Journal of Medical Robotics and Computer Assisted Surgery 15(2), e1985 (2019).
  • Hsiao, F.H., Kuo, W.H., Jow, G.M., Wang, M.Y., Chang, K.J., Lai, Y.M., Chen, Y.T. & Huang, C.S*. The changes of quality of life and their correlations with psychosocial factors following surgery among women with breast cancer from the post-surgery to post-treatment survivorship. The Breast 44, 59-65 (2019).
  • Wu, C.Y., Chen, P.D., Chou, W.H., Liang, J.T., Huang, C.S. & Wu, Y.M. Is robotic hepatectomy cost-effective? In view of patient-reported outcomes. Asian Journal of Surgery 42(4), 543-550 (2019)
  • Lin, C.H., Yap, Y.S., Lee, K.H., Im, S.A., Naito, Y., Yeo, W., Ueno, T., Kwong, A., Li, H., Huang, S.M., Leung, R., Han, W., Tan, B., Hu, F.C., Huang, C.S., Cheng, A.L., Lu, Y.S.. Contrasting Epidemiology and Clinicopathology of Female Breast Cancer in Asians versus the US Population. Journal of the National Cancer Institute 111(12), 1298-1306 (2019)
  • Yang, P.S., Lee, Y.H., Chung, C.F., Chang, Y.C., Wang, M.Y., Lo, C., Tsai, L.W., Shih, K.H., Lei, J., Yu, B.L., Cheng, S.H., Huang, C.S.*. A preliminary Report of Head-to-Head Comparison of 18-Gene-Based Clinical Genomic Model and Oncotype DX 21-Gene Assay for Predicting Recurrence of Early-stage Breast Cancer. Japanese Journal of Clinical Oncology 49(11), 1029-1036 (2019)
  • Petrossian, K., Nguyen, D., Lo, C., Kanaya, N., Somlo, G., Cui, Y.X., Huang, C.S. & Chen, S.A. Use of dual mTOR inhibitor MLN0128 against everolimus-resistant breast cancer. Breast Cancer Research and Treatment 170, 499-506 (2018).
  • Petrossian, K., Kanaya, N., Lo, C., Hsu, P.Y., Nguyen, D., Yang, L., Yang, L., Warden, C., Wu, X., Pillai, R., Bernal, L., Huang, C.S., Kruper, L., Yuan, Y., Somlo, G., Mortimer, J. & Chen, S. ERalpha-mediated cell cycle progression is an important requisite for CDK4/6 inhibitor response in HR+ breast cancer. Oncotarget 9, 27736-27751 (2018).
  • Lai, S.F., Chen, Y.H., Liang, T.H., Hsu, C.Y., Lien, H.C., Lu, Y.S., Huang, C.S. & Kuo, S.H. The breast graded prognostic assessment is associated with the survival outcomes in breast cancer patients receiving whole brain re-irradiation. Journal of Neuro-Oncology 138, 637-647 (2018).
  • Lee, C.Y., Chen, C.M., Wang, H.J., Lai, J.H., Lee, C.E., Lin, F.Y., Chung, M.J., Chang, Y.C. & Huang, C.S.* Longitudinal Infrared Image Registration Without Adhesive Markers for Breast Cancer Chemotherapy Patients. Journal of Medical Imaging and Health Informatics 8, 516-525 (2018).
  • Kuo, S.H., Lo, C., Chen, Y.H., Lien, H.C., Kuo, W.H., Wang, M.Y., Lee, Y.H. & Huang, C.S.* Prognostic Significance of Clinicopathologic Features in Patients With Breast Ductal Carcinoma-in-Situ Who Received Breast-Conserving Surgery. Clinical Breast Cancer 18(6), 441-450 e2 (2018)
  • Bardia, A., Parton, M., Kummel, S., Estevez, L.G., Huang, C.S., Cortes, J., Ruiz-Borrego, M., Telli, M.L., Martin-Martorell, P., Lopez, R., Beck, J.T., Ismail-Khan, R., Chen, S.C., Hurvitz, S.A., Mayer, I.A., Carreon, D., Cameron, S., Liao, S., Baselga, J. & Kim, S.B. Paclitaxel With Inhibitor of Apoptosis Antagonist, LCL161, for Localized Triple-Negative Breast Cancer, Prospectively Stratified by Gene Signature in a Biomarker-Driven Neoadjuvant Trial. Journal of Clinical Oncology 36, 3126-3133 (2018).
  • von Minckwitz, G., Huang, C.S., Mano, M.S., Loibl, S., Mamounas, E.P., Untch, M., Wolmark, N., Rastogi, P., Schneeweiss, A., Redondo, A., Fischer,
  • Dubsky, P., Curigliano, G., Burstein, H.J., Winer, E.P., Gnant, M., Loibl, S., Colleoni, M., Regan, M.M., Piccart-Gebhart, M., Senn, H.J., Thurlimann, B., Andre, F., Baselga, J., Bergh, J., Bonnefoi, H., Brucker, S.Y., Cardoso, F., Carey, L., Ciruelos, E., Cuzick, J., Denkert, C., Di Leo, A., Ejlertsen, B., Francis, P., Galimberti, V., Garber, J., Gulluoglu, B., Goodwin, P., Harbeck, N., Hayes, D.F., Huang, C.S., Huober, J., Khaled, H., Jassem, J., Jiang, Z., Karlsson, P., Morrow, M., Orecchia, R., Osborne, K.C., Pagani, O., Partridge, A.H., Pritchard, K., Ro, J., Rutgers, E.J.T., Sedlmayer, F., Semiglazov, V., Shao, Z., Smith, I., Toi, M., Tutt, A., Viale, G., Watanabe, T., Whelan, T.J., Xu, B. & St Gallen Int Expert, C. Reply to 'The St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2017: the point of view of an International Panel of Experts in Radiation Oncology' by Kirova et al. Annals of Oncology 29, 281-282 (2018).
  • Martin, M., Hurvitz, S.A., Chan, D., Fernandez-Abad, M., Petru, E., Rostorfer, R., Guarneri, V., Huang, C.S., Press, M.F., Costigan, T.M., Caldwell, C.W., Wijayawardana, S., Turner, P.K., Barriga, S. & Slamon, D.J. Final results of NeoMONARCH: A phase 2 neoadjuvant study of abemaciclib in postmenopausal women with hormone receptor positive (HR+), HER2 negative breast cancer (BC). Cancer Research 78, 1 (2018).
  • Huang, Y.S., Takada, E., Konno, S., Huang, C.S., Kuo, M.H. & Chang, R.F. Computer-Aided tumor diagnosis in 3-D breast elastography. Computer Methods and Programs in Biomedicine 153, 201-209 (2018).
  • Hurvitz, S.A., Martin, M., Symmans, W.F., Jung, K.H., Huang, C.S., Thompson, A.M., Harbeck, N., Valero, V., Stroyakovskiy, D., Wildiers, H., Campone, M., Boileau, J.F., Beckmann, M.W., Afenjar, K., Fresco, R., Helms, H.J., Xu, J., Lin, Y.G., Sparano, J. & Slamon, D. Neoadjuvant trastuzumab, pertuzumab, and chemotherapy versus trastuzumab emtansine plus pertuzumab in patients with HER2-positive breast cancer (KRISTINE): a randomised, open-label, multicentre, phase 3 trial. Lancet Oncology 19, 115-126 (2018).
  • Moon, W.K., Chang, J.F., Lo, C.M., Chang, J.M., Lee, S.H., Shin, S.U., Huang, C.S. & Chang, R.F. Quantitative breast density analysis using tomosynthesis and comparison with MRI and digital mammography. Computer Methods and Programs in Biomedicine 154, 99-107 (2018).
  • Lin, C.H., Chuang, P.Y., You, S.L., Chiang, C.J., Huang, C.S., Wang, M.Y., Chao, M., Lu, Y.S., Cheng, A.L. & Tang, C.H. Effect of glucocorticoid use on survival in patients with stage I-III breast cancer. Breast Cancer Research and Treatment 171, 225-234 (2018).
  • Huang, S.C., Wei, P.C., Hwang-Verslues, W.W., Kuo, W.H., Jeng, Y.M., Hu, C.M., Shew, J.Y., Huang, C.S., Chang, K.J., Lee, E. & Lee, W.H. TGF-beta 1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB. EMBO Molecular Medicine 9, 1660-1680 (2017).
  • Curigliano, G., Burstein, H.J., E, P.W., Gnant, M., Dubsky, P., Loibl, S., Colleoni, M., Regan, M.M., Piccart-Gebhart, M., Senn, H.J., Thurlimann, B., St. Gallen International Expert Consensus on the Primary Therapy of Early Breast, C., Andre, F., Baselga, J., Bergh, J., Bonnefoi, H., S, Y.B., Cardoso, F., Carey, L., Ciruelos, E., Cuzick, J., Denkert, C., Di Leo, A., Ejlertsen, B., Francis, P., Galimberti, V., Garber, J., Gulluoglu, B., Goodwin, P., Harbeck, N., Hayes, D.F., Huang, C.S., Huober, J., Hussein, K., Jassem, J., Jiang, Z., Karlsson, P., Morrow, M., Orecchia, R., Osborne, K.C., Pagani, O., Partridge, A.H., Pritchard, K., Ro, J., Rutgers, E.J.T., Sedlmayer, F., Semiglazov, V., Shao, Z., Smith, I., Toi, M., Tutt, A., Viale, G., Watanabe, T., Whelan, T.J. & Xu, B. De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017. Annals of Oncology 28, 1700-1712 (2017).
  • Lee, C.Y., Wang, H.J., Lai, J.H., Chang, Y.C. & Huang, C.S. Automatic Marker-free Longitudinal Infrared Image Registration by Shape Context Based Matching and Competitive Winner-guided Optimal Corresponding. Scientific Reports 7, 16 (2017).
  • Moon, W.K., Lee, Y.W., Huang, Y.S., Lee, S.H., Bae, M.S., Yi, A., Huang, C.S. & Chang, R.F. Computer-aided prediction of axillary lymph node status in breast cancer using tumor surrounding tissue features in ultrasound images. Computer Methods and Programs in Biomedicine 146, 143-150 (2017).
  • Kuo, S.H. & Huang, C.S.* Association between radiosensitivity and molecular subtypes in patients with early-stage breast cancer and lymph node-negative status. Translational Cancer Research 6, S1462-S1466 (2017).
  • Hsiao, F.H., Jow, G.M., Kuo, W.H., Wang, M.Y., Chang, K.J., Lai, Y.M., Chen, Y.T. & Huang, C.S.* A longitudinal study of diurnal cortisol patterns and associated factors in breast cancer patients from the transition stage of the end of active cancer treatment to post-treatment survivorship. The Breast 36, 96-101 (2017).
  • Moon, W.K., Huang, Y.S., Lee, Y.W., Chang, S.C., Lo, C.M., Yang, M.C., Bae, M.S., Lee, S.H., Chang, J.M., Huang, C.S., Lin, Y.T. & Chang, R.F. Computer-aided tumor diagnosis using shear wave breast elastography. Ultrasonics 78, 125-133 (2017).
  • Chow, L.W.C., Biganzoli, L., Leo, A.D., Kuroi, K., Han, H.S., Patel, J., Huang, C.S., Lu, Y.S., Zhu, L., Chow, C.Y.C., Loo, W.T.Y., Gluck, S. & Toi, M. Toxicity profile differences of adjuvant docetaxel/cyclophosphamide (TC) between Asian and Caucasian breast cancer patients. Asia-Pacific Journal of Clinical Oncology 13, 372-378 (2017).
  • Huang, C.S., Yang, Y.W., Chen, R.T., Lo, C.M., Lo, C., Cheng, C.F., Lee, C.S. & Chang, R.F. Whole-Breast Ultrasound for Breast Screening and Archiving. Ultrasound in Medicine and Biology 43, 926-933 (2017).
  • Kuo, S.H., Yang, S.Y., You, S.L., Lien, H.C., Lin, C.H., Lin, P.H. & Huang, C.S.* Polymorphisms of ESR1, UGT1A1, HCN1, MAP3K1 and CYP2B6 are associated with the prognosis of hormone receptor-positive early breast cancer. Oncotarget 8, 20925-20938 (2017).
  • Kuo CS, Chen GR, Hung SH et al. Women with abnormal screening mammography lost to follow-up: An experience from Taiwan. Medicine (Baltimore). 2016 Jun;95(24):e3889( Corresponding author)
  • Chen BB, Lu YS*, Lin CH, Chen WW, Wu PF, Hsu CY, Yu CW, Wei SY, Cheng AL, Shih TT. A pilot study to determine the timing and effect of bevacizumab on vascular normalization of metastatic brain tumors in breast cancer. BMC Cancer. 2016 Jul 13;16:466.
  • Cheng SY, Lin WY, Cheng YH et al. Cancer patient autonomy and quality of dying–aprospective nationwide survey in Taiwan. Psychooncology 2016 Feb;25(2):179-86
  • Chih AH, Su P, Hu WY et al. The Changes of Ethical Dilemmas in Palliative Care. A   Lesson Learned from Comparison Between 1998 and 2013 in Taiwan. Medicine (Baltimore). 2016 Jan; 95(1):e2323.
  • Lai SF, Chen YH , Kuo WH, Lien HC, Wang MY, Lu YS, Lo C,  Kuo SH, Cheng AL, Huang CS. Locoregional Recurrence Risk for Postmastectomy Breast Cancer Patients With T1-2 and One to Three Positive Lymph Nodes Receiving Modern Systemic Treatment Without Radiotherapy. Ann Surg Oncol. 2016 Jul 19.
  • Lin PH, Li HY, Fan SC, Yuan TH, Chen Ming, Hsu YH, Yang YH, Li LY, Yeh SP, Bai LY, Liao YM, Lin CY, Hsieh CY, Lin CC, Lin CH, Lien MY, Chen TT, Ni YH, Chiu CF. A targeted next-generation sequencing in the molecular risk stratification of adult acute myeloid leukemia: implications for clinical practice. Cancer Med. 2016 (accepted)
  • Chou WC, Lin PH, Yeh YC, Shyr YM, Fang WL, Wang SE, Liu CY, Chang PM, Chen MH, Hung YP, CP, Chao Y , Chen MH. Genes involved in angiogenesis and mTOR pathways are frequently mutated in Asian patients with pancreatic neuroendocrine tumors. Int. J. Biol. Sci. 2016 (accepted)
  • Lin PH, Kuo WH, Huang AC, Lu YS, Lin CH, Kuo SH, Wang MY, Liu CY, Cheng FT, Yeh MH, Li HY, Yang YH, Hsu YH, Fan SC, Li LY, Yu SL, Chang KJ, Chen PL, Ni YH, Huang CS. Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer. Oncotarget. 2016 Feb 16;7(7):8310-20. 
  • Wu PF, Lin CH, Kuo CH, Chen WW, Yeh DC, Liao HW, Huang SM, Cheng AL, Lu YS.* A pilot study of bevacizumab combined with etoposide and cisplatin in breast cancer patients with leptomeningeal carcinomatosis. BMC Cancer. 2015 Apr 17;15(1):299. * Correspondence
  • Lu YS, Chen TW, Lin CH, Yeh DC, Tseng LM, Wu PF, Rau KM, Chen BB, Chao TC, Huang SM, Huang CS, Shih TT, Cheng AL; Taiwan Breast Cancer Consortium. Bevacizumab preconditioning followed by Etoposide and Cisplatin is highly effective in treating brain metastases of breast cancer progressing from whole-brain radiotherapy. Clin Cancer Res. 2015 Apr 15;21(8):1851-8.
  • Cheng SY, Suh SY, Morita T et al. A cross-cultural study on behaviors when death is   approaching in East Asian countries: what are the physician-perceived common beliefs and practices? Medicine ( Baltimore). 2015 Sep;94(39):e1573.
  • Shi CY, Hu WY, Cheng SY et al. Patient Preferences versus Family Physicians' Perceptions Regarding the Place of End-of-Life Care and Death: A Nationwide Study in Taiwan. J Palliat Med. 2015 Apr 30
  • Huang HL, Cheng SY, Yao CA et al. Truth Telling and Treatment Strategies in End-of-Life Care in Physician-Led Accountable Care Organizations: Discrepancies Between Patients' Preferences and Physicians' Perceptions. See comment in PubMed Commons belowMedicine (Baltimore). 2015 Apr; 94(16):e657.
  • Morita T, Oyama Y, Cheng SY et al. Palliative Care Physicians' Attitudes Toward Patient Autonomy and a Good Death in East Asian Countries. J Pain Symptom Manage. 2015 Mar 28. pii: S0885-3924(15)00157-8
  • Wu VS, Kanaya N, Lo C, Mortimer J, Chen S. From bench to bedside: What do we know about hormone receptor-positive and human epidermal growth factor receptor 2-positive breast cancer ? J Steroid Biochem Mol Biol. 2015 Sep;153:45-53. doi: 10.1016/j.jsbmb.2015.05.005. Epub 2015 May 18. Review
  • Lien MY, Liu LC, Wang HC, Yeh MH, Chen CJ, Yeh SP, Bai LY, Liao YM, Lin CY, Hsieh CY, Lin CC, Li LY, Lin PH*, Chiu CF. Safety and efficacy of pegylated liposomal doxorubicin-based adjuvant chemotherapy in patients with stage I-III triple-negative breast cancer. Anticancer Res. 2014 Dec;34(12):7319-26 (*correspondence author)
  • Yamaguchi T, Kuriya M, Morita T et al.Palliative care development in the Asia-Pacific region: an international survey from the Asia Pacific Hospice Palliative Care Network (APHN).BMJ Support Palliat Care. 2014 Jul 10.
  • Huang CY, Huang HL, Cheng SY et al. Tour leaders' knowledge of and attitudes toward rabies vaccination, Taiwan. Emerg Infect Dis. 2014 Jan;20(1):157-9.(SCI)
  • Lo C, Shen YW, Huang CS, Chang RF. Computer-aided multiview tumor detection for automated whole breast ultrasound. Ultrason Imaging. 2014 Jan;36(1):3-17
  • C. Lo, P.-C. Lee, R.-F. Yen, C.-S. Huang. Most frequent location of the sentinel lymph nodes. Asian J Surg. 2014 Jul; 37(3):125-9.
  • Lo CM, Chen YP, Chang YC, Lo C, Huang CS, Chang RF. Computer-Aided Strain Evaluation for Acoustic Radiation Force Impulse Imaging of Breast Masses. Ultrason Imaging. 2014 Jun 3; 36(3):151-166.
  • Lee PC, Lo C, Ko WJ, Huang SJ, Lee PH. When and How Should Physicians Determine the Need for Palliative and Hospice Care for Patients With End-Stage Liver Disease? An Experience in Taiwan. Am J Hosp Palliat Care. 2014 Jun; 31(4):454-8.
  • Lee PC, Lo C, Wu JM, Lin KL, Lin HF, Ko WJ. Laparoscopy Decreases the Laparotomy Rate in Hemodynamically Stable Patients With Blunt Abdominal Trauma. Surg Innov. 2014 Apr; 21(2):155-65.
  • Yeh SP, Lo WC, Hsieh CY, Bai LY, Lin CC, Lin PH, Lin CY, Liao YM, Chiu CF. Palonosetron and dexamethasone for the prevention of nausea and vomiting in patients receiving allogeneic hematopoietic stem cell transplantation. Support Care Cancer. 2014 May;22(5):1199-206
  • Chih AH, Lee LT, Cheng SY, Yao CA, Hu WY, Chen CY, Chiu TY. Is it appropriate to withdraw antibiotics in terminal patients with cancer with infection? J Palliat Med. 2013 Nov; 16(11):1417-22.(SCI)
  • Kao CY, Cheng SY, Chiu TY et al. Does the awareness of terminal illness influence cancer patients' psycho-spiritual state, and their DNR signing: a survey in Taiwan. Jpn J Clin Oncol. 2013 Sep;43(9):910-6(SCI)
  • Huang HL, Cheng SY, Lee LT et al. On the trail of preventing meningococcal disease: a survey of students planning to travel to the United States. J Travel Med. 2013 Jul-Aug;20(4):243-6(SCI)
  • Cheng SY, Dy S, Huang SB, Chen CY, Chiu TY. Comparison of proxy ratings of main family caregivers and physicians on the quality of dying of terminally ill cancer patients. Jpn J Clin Oncol. 2013 Aug;43(8):795-804.(SCI)
  • Cheng SY, Dy S, Fang PH, Chen CY, Chiu TY. Evaluation of Inpatient Multidisciplinary Palliative Care Unit on Terminally Ill Cancer Patients from providers' perspectives: A Propensity Score Analysis. Jpn J Clin Oncol 2013 Feb;43(2):161-9.(SCI)
  • Kuo SH, Yang SY, Lien HC, Lo C, Lin CH, Lu YS, Cheng AL, Chang KJ, Huang CS.CYP19 genetic polymorphism haplotype AASA is associated with a poor prognosis in premenopausal women with lymph node-negative, hormone receptor-positive breast cancer.Biomed Res Int. 2013;2013:562197. doi: 10.1155/2013/562197. Epub 2013 Nov 14.
  • Bai LY, Weng JR, Chiu CF, Wu CY, Yeh SP, Sargeant AM, Lin PH, Liao YM. OSU-A9, an indole-3-carbinol derivative, induces cytotoxicity in acute myeloid leukemia through reactive oxygen species-mediated apoptosis. Biochem Pharmacol. 2013 Nov 15;86(10):1430-40.
  • Lin PH, Yeh MH, Liu LC, Chen CJ, Tsui YC, Su CH, Wang HC, Liang JA, Chang HW, Wu HS, Yeh SP, Li YL, Chiu CF. Clinical and pathologic risk factors of tumor recurrence in patients with node-negative early breast cancer after mastectomy. J Surg Onc. 2013 Nov;108(6):352-7.
  • Prognostic analysis of adjuvant chemotherapy in patients with nasopharyngeal carcinoma. Lin CC, Chen TT, Lin CY, Hsieh CY, Lin PH, Chien CR, Chiu CF, Yeh SP. Future Oncol. 2013 Oct;9(10):1469-76.
  • Lin PH, Lin CC, Yang HI, Li LY, Bai LY, Chiu CF, Liao YM, Lin CY, Hsieh CY, Lin CY, Ho CM, Yang SF, Peng CT, Tsai FJ, Yeh SP. Prognostic impact of allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia patients with internal tandem duplication of FLT3. Leuk Res. 2013;37(3):287-92
  • Cheng SY, Dy S, Hu WY, Chen CY, Chiu TY. Factors affecting the improvement of quality of dying of terminally ill cancer patients through palliative care: A ten-year experience. J Palliat Med 2012 Aug; 15(8):854-62. (SCI)
  • 36.   Kuo WH*, Lin PH*, Huang AC, Chien YH, Liu TP, Lu YS, Bai LY, Sargeant A, Lin CH, Cheng AL, Hsieh FJ, Hwu WL, Chang KJ. Multimodel assessment of BRCA1 mutations in Taiwanese (ethnic Chinese) women with early-onset, bilateral or familial breast cancer. J Hum Genet. 2012;57(2):130-8.  (*co-first author)
  • Lin CY, Ho CM, Bau DT, Yang SF, Liu SH, Lin PH, Lin TH, Tien N, Shih MC. Evaluation of Breast Cancer Susceptibility loci on 2q35, 3p24, 17q23 and FGFR2 genes in Taiwanese Women with Breast Cancer. Anticancer Res. 2012;32(2):475-482.
  • Lee PC, Lo C, Lin MT, Liang JT, Lin BR. Role of surgical intervention in managing gastrointestinal metastases from lung cancer. WORLD JOURNAL OF GASTROENTEROLOGY 2011; 17 (38) : 4314-20
  • Huang HL, Chiu TY, Huang KC, Cheng SY, Yao CA, Lee LT. Travel-related mosquito-transmitted disease questionnaire survey among health professionals in Taiwan. J Travel Med 2011 Jan-Feb;18(1):34-8.(SCI)​