▍經歷
- 臺大醫院醫學研究部主治醫師
- 臺大醫院北護分院肝膽腸胃科主治醫師
- 臺大醫院肝膽腸胃科研修醫師
- 臺大醫院內科總醫師
▍主要專長
▍研究方向
- Gut microbiota and cardiometabolic disease
- Gut-liver axis
- Next generation probiotics
▍近五年論文發表
- Wei-Kai Wu, Ekaterina A Ivanova, Alexander N Orekhov. Gut microbiome: A possible common therapeutic target for treatment of atherosclerosis and cancer. Seminars in Cancer Biology. 2021 May;70:85-97. DOI: 10.1016/j.semcancer.2020.06.017.
- Wei-Kai Wu, Yi-Hsun Chen, Po-Chu Lee, Po-Jen Yang, Chin-Chen Chang, Kao-Lang Liu, Cheng-Chih Hsu, Chi-Chang Huang, Hsiao-Li Chuang, Lee-Yan Sheen, Chun-Jen Liu and Ming-Shiang Wu. Mining Gut Microbiota from Bariatric Surgery for MAFLD. Frontiers in Endocrinology. 2021 Apr 9;12:612946. DOI: 10.3389/fendo.2021.612946.
- Chieh-Chang Chen, Wei-Kai Wu, Chih-Min Chang, Suraphan Panyod, Tzu-Pin Lu, Jyh-Ming Liou, Yu-Jen Fang, Eric Y Chuang, Ming-Shiang Wu (2020, Feb). Comparison of DNA stabilizers and storage conditions on preserving fecal microbiota profiles. Journal of the Formosan Medical Association. 2020 Dec;119(12):1791-1798. DOI: 10.1016/j.jfma.2020.01.013.
- Chih-Fan Yeh, Ying-Hsien Chen, Sheng-Fu Liu, Hsien-Li Kao, Ming-Shiang Wu, Kai-Chien Yang, Wei-Kai Wu*. Mutual Interplay of Host Immune System and Gut Microbiota in the Immunopathology of Atherosclerosis. International Journal of Molecular Sciences. 2020 Nov 19;21(22):8729. DOI: 10.3390/ijms21228729. *Corresponding author
- Wei-Kai Wu, Suraphan Panyod, Po-Yu Liu, Chieh-Chang Chen, Hsien-Li Kao, Hsiao-Li Chuang, Ying-Hsien Chen, Hsin-Bai Zou, Han-Chun Kuo, Ching-Hua Kuo, Ben-Yang Liao, Tina H T Chiu, Ching-Hu Chung, Angela Yu-Chen Lin, Yi- Chia Lee, Sen-Lin Tang, Jin-Town Wang, Yu-Wei Wu, Cheng-Chih Hsu, Lee- Yan Sheen, Alexander N Orekhov, Ming-Shiang Wu. Characterization of TMAO productivity from carnitine challenge facilitates personalized nutrition and microbiome signatures discovery. Microbiome. 2020 Nov 19;8(1):162. DOI: 10.1186/s40168-020-00912-y.
- Wei-Kai Wu, Jyh-Ming Liou, Cheng-Chih Hsu, Yung-Hsiang Lin, Ming-Shiang Wu. Pandemic preparedness in Taiwan. Nature Biotechnology. 2020 Aug;38(8):932-933. DOI: 10.1038/s41587-020-0630-0.
- Wei-Kai Wu, Cheng-Chih Hsu, Lee-Yan Sheen, Ming-Shiang Wu. Measurement of Gut Microbial Metabolites in Cardiometabolic Health and Translational Research. Rapid Communications in Mass Spectrometry. 2020 Apr;34 Suppl 1:e8537. DOI: 10.1002/rcm.8537.
- Wei-Kai Wu, Lee-Yan Sheen, Ming-Shiang Wu. Response to the letter: Identification of trimethylamine N-oxide (TMAO)-producer phenotype is interesting, but is it helpful?. Gut. 2020 Mar;69(3):610-611. DOI: 10.1136/gutjnl-2018-318187.
- Suraphan Panyod, Wei-Kai Wu, Kuan-Hung Lu, Chun-Ting Liu, Yung-Lin Chu, Chi-Tang Ho, Wen Luan Wendy Hsiao, Ming-Shiang Wu, Yi-Syuan Lai, Wei- Cheng Chen, Yu-En Lin, Shi-Hang Lin, Lee-Yan Sheen. Allicin Modifies the Composition and Function of the Gut Microbiota in Alcoholic Hepatic Steatosis Mice. Journal of Agricultural and Food Chemistry, 2020 Mar 11;68(10):3088-3098. DOI: 10.1021/acs.jafc.9b07555.
- Wei-Kai Wu, Chieh-Chang Chen, Po-Yu Liu, Suraphan Panyod, Ben-Yang Liao, Pei-Chen Chen, Hsien-Li Kao, Han-Chun Kuo, Ching-Hua Kuo, Tina H T Chiu, Rou-An Chen, Hsiao-Li Chuang, Yen-Te Huang, Hsin-Bai Zou, Cheng-Chih Hsu, Ting-Yan Chang, Chin-Lon Lin, Chi-Tang Ho, Hon-Tsen Yu, Lee-Yan Sheen, Ming-Shiang Wu. Identification of TMAO-producer phenotype and host-diet-gut dysbiosis by carnitine challenge test in human and germ-free mice. Gut. 2019 Aug;68(8):1439-1449. DOI: 10.1136/gutjnl-2018-317155.
- Ya-Lin Hsu, Chieh-Chang Chen, Ya-Ting Lin, Wei-Kai Wu, Lin-Chau Chang, Chang-Hao Lai, Ming-Shiang Wu, Ching-Hua Kuo (2019, Mar). Evaluation and optimization of sample handling methods for quantification of short-chain fatty acids in human fecal samples by GC-MS.. Journal of Proteome Research. 2019 May 3;18(5):1948-1957. DOI: 10.1021/acs.jproteome.8b00536.
- Wei-Kai Wu, Chieh-Chang Chenc, Suraphan Panyod, Rou-An Chen, Ming- Shiang Wu, Lee-Yan Sheen, Shan-Chwen Chang. Optimization of Fecal Sample Processing for Microbiome Study — The Journey from Bathroom to Bench. Journal of the Formosan Medical Association. 2019 Feb;118(2):545-555. DOI: 10.1016/j.jfma.2018.02.005.
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