▍經歷
- 國立臺灣大學醫學院(附設醫院)醫學研究部 助理研究員
- 國立臺灣大學醫學院 臨床醫學研究所 博士後研究員
▍主要專長
▍研究方向
- 疫苗及佐劑研發
- 抗病毒藥物研發
- 腫瘤治療
- 靈芝免疫調節之研究
- 天然抗氧化物之研究
▍近五年論文發表
- Chen JL, Pan CK, Lin LC, Tsai CY, Kuo CY, Huang YS, Lin YL*.Therapeutic Efficacy of Cyclin-Dependent Kinase Inhibition in Combination with Ionizing Radiation for Lung Cancer. International Journal of Radiation Biology 2022 Dec 14 (Accept)
- Chen JL, Pan CK, Lin YL*, Tsai CY, Huang YS, Yang WC, Hsu FM, Kuo SH, Shieh MJ. Preclinical evaluation of PEGylated liposomal doxorubicin as an effective radiosensitizer in chemoradiotherapy for lung cancer. Strahlenther Onkol. 197(12):1131-1142, 2021. doi: 10.1007/s00066-021-01835-9.
- Chen JL, Pan CK, Huang YS, Tsai CY, Wang CW, Lin YL*, Kuo SH, Shieh MJ. Evaluation of antitumor immunity by a combination treatment of high-dose irradiation, anti-PDL1, and anti-angiogenic therapy in murine lung tumors. Cancer Immunology, Immunotherapy 70(2):391-404, 2021. DOI: 10.1007/s00262-020-02690-w.
- Lin YL, Shih C, Cheng PY, Chin CL, Liou AT, Lee PY, Chiang BL*. A polysaccharide purified from Ganoderma lucidum acts as a potent mucosal adjuvant that promotes protective immunity against the lethal challenge with Enterovirus A71. Frontiers in Immunology 11:561758, 2020. DOI: 10.3389/fimmu.2020.561758.
- Chen JL, Shen CW, Wang CC, Huang YS, Chen JP, Chiang CH, Lin YL, Kuo SH, Wang CW*. Impact of smoking cessation on clinical outcomes in patients with head and neck squamous cell carcinoma receiving curative chemoradiotherapy: A prospective study. Head Neck, 41(9):3201-3210, 2019. DOI: 10.1002/hed.25814.
- Chen JL, Chang CC, Huang YS, Kuo HY, Chen TY, Wang CW, Kuo SH, Lin YL*. Persistently elevated soluble MHC class I polypeptide-related sequence A and transforming growth factor-β1 levels are poor prognostic factors in head and neck squamous cell carcinoma after definitive chemoradiotherapy. PLoS One, 13(8):e0202224, 2018. DOI: 10.1371/journal.pone.0202224.
- Jan RH, Chen CJ, Hong YR, Lin YL*, Chen LK*. A surface antigen of Orientia tsutsugamushi activates human monocyte-derived dendritic cells via nuclear factor-kB & p38 mitogen-activated protein kinase pathways. Indian J Med Res, 148 (2): 215-224, 2018. DOI: 10.4103/ijmr.IJMR_1417_16.
- Lin YL, Cheng PY, Chin CL, Huang LM, Lin SY, Chiang BL*. Fibroblast-stimulating lipopeptide-1 as a potential mucosal adjuvant enhances mucosal and systemic immune responses to enterovirus 71 vaccine. Vaccine, 36(29):4331-4338, 2018. DOI: 10.1016/j.vaccine.2018.05.090.
- Lin YL, Chow YH, Huang LM, Hsieh SM, Cheng PY, Hu KC, Chiang BL*. A CpG-adjuvanted intranasal enterovirus 71 vaccine elicits mucosal and systemic immune responses and protects human SCARB2-transgenic mice against lethal challenge. Scientific Reports, 8(1):10713, 2018. DOI: 10.1038/s41598-018-28281-5.
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